中药对肠促胰岛素影响的研究进展
2018,50(2):135-139
摘要：肠促胰岛素包括葡萄糖依赖性促胰岛素多肽（GIP）和胰高血糖素样肽-1（GLP-1），二者均能促进β细胞增殖、刺激胰岛素分泌、调节食欲，从而发挥降糖作用。随着对肠促胰岛素的不断认识，中药对肠促胰岛素影响的临床研究越来越多。笔者从中药有效成份、单味药、中药复方对肠促胰岛素的影响等方面进行综述，以期为筛选疗效更好的糖尿病中药提供参考。
关键词：肠促胰岛素；糖尿病；中药疗法；葡萄糖依赖性促胰岛素多肽；胰高血糖素样肽一1
Research Progress of the Effect of Chinese Medicine on Incretin
Abstract：Incretin includes glucose-dependent insulinotropic polypeptide(GIP)and glucagon-like peptide-1(GLP-1)，bothof which can improve the proliferation of β cell， stimulate secretion of insulin and regulate appetite so as to decrease the glucose.As the understanding of incretin continues to deepen，there are more and more clinical studies with regard to the effect of Chinese medicine on incretin.The authors reviewed the effect of effective constituents in Chinese medicine，single medicine，and Chinese herbal compound on incretin in an attempt to provide references for the selection of more effective Chinese medicine for diabetes mellitus.
Key words：Incretin；Diabetes mellitus；Chinese medicine therapy；Glucose-dependent insulinotropic polypeptide(GIP)；Glucagon-like peptide-1
收稿日期：
基金项目：国家中医药管理局中医药标准化项目(SATCM-2015-B2278)
