肝-肾-脾序贯调周法治疗卵巢储备功能低下临床研究
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R711.75

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Clinical Study of Sequential Cycle Adjustment Therapy of Liver-Kidney-Spleen for Dysfunction of Ovarian Reserve
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    摘要:

    目的:观察肝-肾-脾序贯调周法治疗卵巢储备功能低下(DOR)的临床疗效。方法:选取78例DOR患者为研究对象,随机分为治疗组40例和对照组38例。治疗组采用肝-肾-脾序贯调周法治疗,对照组给予克龄蒙治疗。观察2组治疗前后症状积分及血清性激素指标[促卵泡激素(FSH)、促黄体生成素(LH)、抗苗勒氏管激素(AMH)]水平的变化,评估治疗效果。结果:治疗后,2组月经量少积分及症状总积分均较治疗前降低(P<0.05);治疗组的月经量少积分及症状总积分均较对照组下降更明显(P<0.05)。治疗后,2组FSH、LH水平均较治疗前降低(P<0.05),AMH水平均较治疗前升高(P<0.05);组间3项性激素指标水平比较,差异均无统计学意义(P>0.05)。治疗组总有效率90.0%,对照组总有效率71.0%,2组比较,差异有统计学意义(P<0.05)。结论:肝-肾-脾序贯调周法治疗DOR,可有效改善患者的月经周期、月经量,调节性激素指标,效果优于克龄蒙治疗。

    Abstract:

    Objective: To observe the clinical effect of sequential cycle adjustment therapy of liver-kidney-spleen for dysfunction of ovarian reserve(DOR).Methods:Selected 78 cases of DOR patients as study subjects,and randomly divided them into the treatment group and the control group,respectively 40 cases and 38 cases in each group.The treatment group was given sequential cycle adjustment therapy of liver-kidney-spleen,while the control group receivedClimen for treatment.Observed the changes of symptom score as well as levels of serum sex hormone indexes[follicle-stimulating hormone(FSH),luteinizing hormone(LH)and anti-mullerian hormone(AMH)]in both groups before and after treatment,and evaluated the curative effect.Results:After treatment,hypomenorrhea scores and total symptom scores in both groups were lower than those before treatment(P<0.05),and the two scores in the treatment group were both declined more evidently than those in the control group(P<0.05).After treatment,levels of FSH and LH in the two groups were both lower than those before treatment(P<0.05),while AMH levels in both groups were higher than those before treatment(P<0.05).The comparisons of the levels of three sex hormone indexes between the two groups showed no significance in differences(P>0.05).The total effective rate was 90.0%in the treatment group and 71.0%in the control group,the difference being significant(P<0.05).Conclusion:The sequential cycle adjustment therapy of liver-kidney-spleen for dysfunction of ovarian reserve can effectively improve menstrual cycle and menstrual quantity of patients as well as regulate sex hormone indexes,being more effective than Climen therapy.

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郭雯雯,胡子衡,苏丽嬛,李小梅.肝-肾-脾序贯调周法治疗卵巢储备功能低下临床研究[J].新中医,2017,49(12):89-91

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  • 在线发布日期: 2017-12-02
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