Objective:To observe the clinical effect of Fuzheng Xiaoliu tang on gastric cancer patients and angiogenesisinhibition in tumor tissue.Methods:Selected 80 gastric cancer patients, and divided them into two groups according to random table method, 40 cases in each group.The control group receivedchemotherapy of FAM, while the observation group was given modified Fuzheng Xiaoliu tang based on the treatment of the control group.Compared and observed clinical effect of two groups and effect of Fuzheng Xiaoliu tang on angiogenesis inhibition.Results:Compared clinical effect of the two groups,the total effective rate was 70.0%in the control group and was 92.5%in the observation group, the difference being significant(P<0.05).After treatment,compared IgA,IgG of the treatment group with those of the control group respectively,differences being significant(P<0.05).The concentration of serum vascular endothelial growth factor(VEGF)in both groups was lower than that before,the difference being significant(P<0.05),and the difference between the two groups was significant(P<0.05).After treatment,compared self-conscious symptom, physical and functional status of body,daily life,social activities and total scores of quality of life scale in the observation group with that those in the control group, differences being significant(P<0.05).Conclusion:Fuzheng Xiaoliu tang is effective for gastric cancer and has a good inhibitive effect on VEGF of late gastric cancer patients,which is worth of clinical application.