参松养心胶囊联合维生素D辅助治疗原发性高血压临床研究
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R544.1

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Clinical Study of Shensong Yangxin Capsules Combined with Vitamin D in Adjunctive Therapy for Primary Hypertension
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    摘要:

    目的:观察参松养心胶囊联合维生素D辅助治疗原发性高血压的临床疗效。方法:选取112例原发性高血压患者,按照随机数字表法分为对照组和观察组各56例。2组患者均给予常规抗高血压药物及维生素D进行治疗,观察组加用参松养心胶囊治疗,2组均连续治疗4周。比较2组的临床疗效、症状疗效,观察血清中25羟基维生素D3含量的变化及用药安全性等。结果:治疗后,临床疗效总有效率对照组76.8%,观察组94.6%,2组比较,差异有统计学意义(P<0.05)。观察组头痛、眩晕、失眠、四肢无力的改善情况均优于对照组,差异均有统计学意义(P<0.05)。2组均未出现较明显的不良反应,安全性较好。结论:在常规治疗基础上加用参松养心胶囊联合维生素D辅助治疗原发性高血压,可有效控制血压,改善临床症状,提高临床疗效,且安全性较好。

    Abstract:

    Objective:To observe the clinical curative effect of Shensong Yangxin capsules combined with vitamin D in adjunctive therapy for primary hypertension.Methods:Selected 112 cases of patients with primary hypertension,and divided them into the control group and the observation group randomly according to random number table,56 cases in each group.Patients in both groups were given routine dyazide and vitamin D,while the observation group was additionally receivedShensong Yangxin capsules.Treatment for both groups lasted for 4 weeks.Compared the clinical curative effect and symptomatic effect,and observed the content changes of 25-hydroxy vitamin D3in serum and its safety,etc.Results:After treatment,the total effective rate of clinical curative effect was 76.8%in the control group and 94.6%in the observation group,the difference being significant(P< 0.05).The improvements of headache,dizziness,insomnia,and myasthenia of limbs in the observation group were better than those in the control group,differences being significant(P<0.05).There was no obvious adverse reaction in both groups,which suggested the safety of the therapies.Conclusion:Based on routine therapy,the additional application of Shensong Yangxin capsules combined with vitamin D in adjunctive therapy for primary hypertension can evidently control the blood pressure and improve clinical curative effect with preferable safety.

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诸帆.参松养心胶囊联合维生素D辅助治疗原发性高血压临床研究[J].新中医,2018,50(1):23-25

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  • 在线发布日期: 2018-01-05
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