清胰汤加减联合空肠营养治疗对重症急性胰腺炎腹内压及预后的影响
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Effect of Modified Qingyi Tang Combined with Jejunal Nutrition Therapy on Intraabdominal Pressure and Prognosis of Severe Acute Pancreatitis
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    摘要:

    目的:观察清胰汤加减联合空肠营养治疗对重症急性胰腺炎腹内压及预后的影响。方法:将94 例重症急性胰腺炎患者随机分为对照组与观察组,对照组采用常规治疗,观察组在对照组治疗基础上采用清胰汤加减联合空肠营养治疗。观察2 组疗效、症状、腹内压及相关指标变化。结果:观察组住院时间、腹胀持续时间、血清淀粉酶恢复时间以及肠功能恢复时间均优于对照组,差异有统计学意义(P<0.01)。观察组腹内压、白细胞计数、C-反应蛋白、降钙素原均优于对照组,差异有统计学意义(P<0.01)。观察组治疗总有效率为97.87%,高于对照组的80.85%,差异有统计学意义(P<0.01)。结论:清胰汤加减联合空肠营养治疗重症急性胰腺炎患者不仅可有效的降低患者腹内压,减少腹胀持续时间,加快血清淀粉酶及肠功能恢复时间,抑制炎症反应,还可提高临床疗效及预后。

    Abstract:

    Abstract: Objective: To observe the effect of modified Qingyi tang combined with jejunal nutrition therapy on intraabdominal pressure and prognosis of severe acute pancreatitis. Methods:A total of 94 cases of patients with severe acute pancreatitis were randomly divided into the control group and the observation group. The control group was treated with routine therapy,and the observation group was additionally treated with modified Qingyi tang combined with jejunal nutrition therapy based on the treatment of the control group. The changes in curative effect,symptoms,intra-abdominal pressures and relative indexes in the two groups were observed. Results:The length of hospital stay,duration of abdominal distension and the recovery time of serum amylase as well as intestinal function in the observation group were better than those in the control group,the difference being significant(P<0.01). The intra-abdominal pressure,white blood cell counts,C-reactive protein and procalitonin in the observation group were all better than those in the control group, the difference being significant(P<0.01). The curative effective rate was 97.87% in the observation group, higher than that of 80.85% in the control group, the difference being significant(P<0.01). Conclusion: Modified Qingyi tang combined with jejunal nutrition therapy for patients with severe acute pancreatitis can effectively reduce their intra-abdominal pressures and the duration of abdominal distension, accelerate the recovery time of serum amylase and intestinal function, inhibit the inflammatory responses,and can improve the clinical effect and prognosis.

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李生奇,王昊峰,蒋嘉尧,马俊骅,尚德民.清胰汤加减联合空肠营养治疗对重症急性胰腺炎腹内压及预后的影响[J].新中医,2020,52(17):78-80

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  • 在线发布日期: 2020-09-06
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