肾衰宁胶囊联合中医护理治疗慢性肾衰竭早中期临床研究及对肾功能的影响
DOI:
作者:
作者单位:

作者简介:

通讯作者:

中图分类号:

R692.5

基金项目:


Clinical Study on Shenshuaining Capsules Combined with Chinese Medicine Nursing for Chronic Renal Failure in Early and Middle Stage and Its Effect on Kidney Function
Author:
Affiliation:

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    目的:观察肾衰宁胶囊和中医护理联合治疗对慢性肾衰竭(CRF) 早中期患者的临床价值。方法:将102 例的CRF早中期患者随机分为对照组和观察组,每组51 例。对照组给予常规治疗和护理,观察组在此基础上给予肾衰宁胶囊和中医护理联合治疗,对比2 组患者干预前后的临床症状积分、血红蛋白(Hb)、白蛋白(Alb)、24 h 尿蛋白定量(24 h UPQ)、尿酸(UA)、血肌酐(SCr),血尿素氮(BUN)、肌酐清除率(CCr)、血清胱抑素-C(Cys-C) 水平。结果:2 组干预前临床症状各项积分比较,差异无统计学意义(P>0.05);对照组干预后食少纳呆、肢体麻木、口淡不渴积分较干预前降低,观察组干预后各项临床症状积分与干预前比较明显较低,改善程度优于对照组,差异有统计学意义(P<0.05)。2 组干预前Hb、Alb、24 h UPQ、UA 含量比较,差异无统计学意义(P>0.05);对照组干预后Hb、Alb、24 h UPQ 含量明显降低,观察组干预后24 h UPQ 含量降低,降低程度大于对照组,差异有统计学意义(P<0.05)。2 组干预前SCr,BUN、CCr、Cys-C 水平比较,差异无统计学意义(P>0.05);对照组干预后Cys-C 水平降低,观察组干预后SCr、BUN、Cys-C 较干预前低,CCr 较干预前高,改善程度高于对照 组,差异有统计学意义(P<0.05)。结论:CRF 早中期患者采用肾衰宁胶囊和中医护理联合治疗,能可明显缓解临床症状,改善肾功能。

    Abstract:

    Abstract:Objective:To observe the clinical value of Shenshuaining capsules combined with Chinese medicine nursing for chronic renal failure(CRF) in early and middle stage. Methods: A total of 102 cases of CRF patients in early and middle stage were randomly divided into the control group and the observation group,51 cases in each group. The control group was given routine treatment and nursing, and the observation group was additionally given Shenshuaining capsules combined with Chinese medicine nursing based on the treatment of the control group. Before and after treatment,the scores of clinical symptoms and the levels of hemoglobin(Hb),albumin(Alb),24- hour urine protein quantification(24 h UPQ),uric acid(UA) serum creatinine(SCr), blood urea nitrogen(BUN), creatinine clearance rate(CCr) and serum cystatin C(Cys- C) in the two groups were compared. Results: Before treatment, there was no significant difference being found in the comparison of scores of clinical symptoms between the two groups(P>0.05). After treatment,the scores of poor appetite,limb numbness and tastelessness and hydroadipsia in the two groups were decreased when compared with those before treatment,and the decrease in the observation group was more significant than that in the control group, and the improvement in the observation group was better, the difference being significant(P<0.05). Before treatment, there was no significant difference being found in the comparison of the contents of Hb,Alb,24 h UPQ and UA between the two groups(P>0.05). After treatment, the contents of Hb, Alb and 24h UPQ in the control group were significantly decreased when compared with those before treatment,and the 24 h UPQ content in the observation group was decreased,and the decrease in the observation group was larger than that in the control group, the difference being significant(P<0.05). Before treatment, there was no significant difference being found in the comparison of levels of SCr,BUN,CCr and Cys-C between the two groups(P>0.05). After treatment, the Cys- C level in the control group was decreased when compared with that before treatment,and the levels of SCr,BUN and Cys-C in the observation group were significantly decreased,and the CCr level was increased; the improvement in the observation group was better than that in the control group, the difference being significant(P<0.05). Conclusion:The application of Shenshuaining capsules combined with Chinese medicine nursing for CRF patients in early and middle stage can significantly relieve clinical symptoms and improve kidney function.

    参考文献
    相似文献
    引证文献
引用本文

刘霄燕.肾衰宁胶囊联合中医护理治疗慢性肾衰竭早中期临床研究及对肾功能的影响[J].新中医,2020,52(17):146-149

复制
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期: 2020-09-06
  • 出版日期: