知柏地黄汤联合盐酸二甲双胍片治疗阴虚火旺型2型糖尿病临床观察
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R587.1

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Clinical Observation of Zhibai Dihuang Tang Combined with Metformin Hydrochloride Tablets for Type 2 Diabetes of Fire Hyperactivity Due to Yin Deficiency Type
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    摘要:

    目的:观察知柏地黄汤联合盐酸二甲双胍片治疗阴虚火旺型2型糖尿病的临床疗效。方法:选取166例阴虚火旺型2型糖尿病患者,随机分为对照组和治疗组各83例。对照组采用口服盐酸二甲双胍片配合基础治疗,治疗组在对照组用药基础上加服知柏地黄汤。治疗2月后,对患者的各项中医症状进行评分,测定糖化血红蛋白含量,评估治疗效果。结果:治疗组总有效率93.98%,对照组总有效率74.70%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组糖化血红蛋白水平均较治疗前降低(P<0.05);治疗组的糖化血红蛋白水平低于对照组(P<0.05)。治疗组糖化血红蛋白水平治疗前后差值大于对照组(P<0.05)。治疗后,2组咽干口燥、心烦失眠、口渴喜饮、腰膝酸软、潮热盗汗、大便干结积分及中医症状总积分均较治疗前降低(P<0.05);治疗组6项中医症状积分及中医症状总积分均低于对照组(P<0.05)。与对照组比较,治疗组中医症状总积分治疗前后的差值较大(P<0.05)。结论:知柏地黄汤联合盐酸二甲双胍片治疗阴虚火旺型2型糖尿病,可显著改善患者的症状,提高临床疗效。

    Abstract:

    Objective:To observe the clinical effect of Zhibai Dihuang tang combined with metformin hydrochloride tablets for type 2 diabetes of fire hyperactivity due to yin deficiency type.Methods:Divided 166 cases of patients with type 2 diabetes of fire hyperactivity due to yin deficiency type into the control group and the treatment group randomly,83 cases in each group.Both groups were given metformin hydrochloride tablets and basic treatment,while the treatment group additionally receivedZhibai Dihuang tang.After two months of treatment,scored each Chinese medicine symptom in the patients,detected glycosylated hemoglobin content and evaluated the curative effect.Results:The total effective rate was 93.98% in the treatment group and was 74.70% in the control group,the difference being significant(P<0.05).After treatment,glycosylated hemoglobin levels in both groups were lower than those before treatment;glycosylated hemoglobin levels in the treatment group were lower than those in the control group(P<0.05);the difference of glycosylated hemoglobin levels before and after treatment in the treatment group was higher than that in the control group(P<0.05).After treatment,scores of dry mouth and throat,vexation and insomnia,thirst,soreness-tired of waist and knee,hot flush and night sweat,constipation and the total Chinese medicine symptom scores in both groups were lower than those before treatment(P<0.05).Six terms of Chinese medicine symptom scores and the total Chinese medicine symptom scores in the treatment group were lower than those in the control group(P<0.05).Comparing with the control group,the difference of total Chinese medicine symptom scores before and after treatment in the treatment group was higher(P<0.05).Conclusion:Zhibai Dihuang tang combined with metformin hydrochloride tablets for type 2 diabetes offire hyperactivity due to yin deficiency type can effectively improve symptoms of patients and enhance the clinical effect.

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关伟泽.知柏地黄汤联合盐酸二甲双胍片治疗阴虚火旺型2型糖尿病临床观察[J].新中医,2018,50(1):57-59

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  • 在线发布日期: 2018-01-05
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