电针治疗面肌痉挛临床有效性评价及 Meta 分析
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R245.31

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国家自然科学基金项目(81673888);广东省中医院中医药科学技术研究专项(YN2015QN19);广东省教育厅青年创新人才项目(2016KQNCX27)


Evaluation of Clinical Efficiency and Meta-analysis on Electroacupuncture for Hemifacial Spasm
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    摘要:

    目的:评价电针治疗面肌痉挛随机对照试验的有效性。方法:通过电子检索中国科技期刊全文数据库(VIP)、万方数据库(Wanfang)、中国知网(CNKI)、中国生物医学文献数据库(CBM)、PubMed、EMbase、Medline数据库,检索时间从各数据库建库至2017年11月30日。对纳入的关于电针治疗面肌痉挛的临床随机对照试验进行质量评价,并对电针治疗面肌痉挛的有效性进行Meta分析。结果:共纳入16个临床随机试验,面肌痉挛患者合计1154例,含治疗组619例,对照组535例。Meta分析结果表明,电针组总有效率[OR=5.54,95%CI(3.91,7.84),P<0.01],明显优于非电针组。亚组分析结果表明,电针组明显优于体针组 [OR=5.53,95%CI(2.83,10.81),P <0.01],电针组优于西药组 [OR=5.48,95%CI(2.28,13.13),P < 0.01],电针综合组优于药物组[OR=4.29,95%CI(1.08,17.03),P<0.05]。结论:电针治疗面肌痉挛疗效可观,值得作为一种物理疗法在临床上推广。但因纳入文献质量较低,仍需进一步完善针灸临床研究设计,开展高质量的临床研究。

    Abstract:

    Objective:To evaluate the efficiency of electroacupuncture for hemifacial spasm in randomized controlled trials.Methods: Searched Chinese Sci-Tech Periodical Full-Text Database(VIP), Wanfang Database(Wanfang), China National Knowledge Infrastructure(CNKI),Chinese Biological Medical Disc(CBM),PubMed,EMbase and Medline Database.Searched for the literature from the establishment time of each database to 30th,November 2017.Evaluated the quality of selected clinical randomized controlled trials of electroacupuncture for hemifacial spasm and conducted Meta-analysis on the efficiency of electroacupuncture for hemifacial spasm.Results:Sixteen clinical randomized controlled trials were included,including 1154 cases of patients with hemifacial spasm,619 cases in the treatment group and 535 cases in the control group.The result of Meta-analysis showed that the total effective rate of the electroacupuncture group[OR=5.54,95%CI(3.91,7.84),P<0.01]was superior to that of the group which did not received electroacupuncture.The result of subgroups showed that the total effective rate of the electroacupuncture group was obviously superior to that of the hand acupuncture group[OR=5.48,95%CI(2.28,13.13),P < 0.01]and that of the western medicine group[OR=5.48,95%CI(2.28,13.13),P < 0.01].The total effective rate of the electroacupuncture integration group was superior to that of the medicine group[OR=4.29,95%CI(1.08,17.03),P < 0.05].Conclusion:The efficiency of electroacupuncture for hemifacial spasm is considerable and it is worthy of clinical promotion as a kind of physical therapy.However,due to the low quality of selected literature,the clinical research and design of acupuncture and moxibustion still need to be further perfected and the clinical research of higher quality need to be conducted.

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黄键澎,郭小川,刘健华.电针治疗面肌痉挛临床有效性评价及 Meta 分析[J].新中医,2018,50(6):28-32

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  • 在线发布日期: 2018-06-05
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