和胃扶正三联疗法治疗非小细胞肺癌化疗相关性恶心呕吐临床观察
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R442.1;R818,051

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河南省高等学校重点研究项目(18A360010)


Clinical Observation of Triple Therapy of Regulating the Stomach and Streng the ning Body Resistance for Chemotherapy-induced Nausea and Vomiting after Non-small Cell Lung Cancer Chemotherapy
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    摘要:

    目的:观察自拟和胃扶正散外用脐疗联合透灸足三里、吴茱萸贴敷涌泉三种疗法联合治疗非小细胞肺癌化疗相关性恶心呕吐(CINV)的疗效。方法:将56例患者按随机数字表法随机分为2组,对照组于化疗开始应用托烷司琼注射液预防性治疗,治疗组在对照组治疗方案的基础上加用和胃扶正散脐疗,回旋灸透灸足三里及吴茱萸贴敷涌泉穴的三联疗法,2组均治疗6天为1疗程。结果:2组治疗后消化道反应分级情况比较,差异有统计学意义(P<0.05),治疗组优于对照组。2组临床疗效比较,总有效率治疗组9 2.9%,对照组85.7%,差异有统计学意义(P<0.05)。治疗后,治疗组前白蛋白水平高于对照组,差异有统计学意义(P<0.05)。治疗后,治疗组恶心呕吐、食欲丧失症状评分与对照组比较,差异均有统计学意义(P<0.05);与对照组比较,在躯体功能、情绪功能、腹泻上的评分,差异均无统计学意义(P>0.05)。结论:和胃扶正三联疗法治疗非小细胞肺癌化疗后CINV临床疗效良好,能改善患者生活质量及延缓营养状况的下降。

    Abstract:

    Objective:To observe the clinical effect of the self-made triple therapy of the external application of umbilical moxibustion with Hewei Fuzheng powder combined with penetrating moxibustion at Zusanli and point application with evodia rutaecarpa at Yongquan for chemotherapy-induced nausea and vomiting(CINV)after non-small cell lung cancer chemotherapy.M e th o d s:Divided 56 cases of patients into two groups,namely the control group and the treatment group.Both groups were applied with tropisetron injection for preventive treatment,while the treatment group additionally received the triple therapy of umbilical moxibustion with Hewei Fuzheng powder,penetrating moxibustion at Zusanli and point application with evodia rutaecarpa at Yongquan.The treatment for both groups lasted for one course of 6 days.Results:Comparing the classification of digestive tract reactions in both groups after treatment,there was significant difference being found(P < 0.05).Comparing the clinical effect in both groups,the total effective rate was 92.9%in the treatment group and 85.7%in the control group,difference being significant(P < 0.05).After treatment,the level of prealbumin in the treatment group was lower than that in the control group,difference being significant(P < 0.05).After treatment,when comparing with the control group,the treatment group could improve the symptoms of nausea,vomiting and appetite loss,differences being significant(P < 0.05);comparing the scores of emotional function,physical function and diarrhea in the treatment group with those in the control group,there were no significant differences being found(P< 0.05).Conclusion:The triple therapy of regulating the stomach and strengthening body resistance has a good clinical effect in treating CINV after non-small cell lung cancer chemotherapy,which can improve the quality of life of patients and delay the decline of nutritional status.

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杨秦梅,崔青荣,李彬,周庆伟.和胃扶正三联疗法治疗非小细胞肺癌化疗相关性恶心呕吐临床观察[J].新中医,2018,50(6):176-179

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  • 在线发布日期: 2018-06-05
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