龙竭散外敷治疗消化道恶性肿瘤癌性疼痛临床研究
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R441.1;R730.6

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2015年江苏省中医药科技项目(YB2015147)


Clinical Study on External Application of Longjie Powder for Cancer Pain of Digestive Tract Malignant Tumor
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    摘要:

    目的:观察龙竭散外敷疼痛处治疗消化道恶性肿瘤癌性疼痛的临床疗效。方法:将87例患者随机分为观察组54例,对照组3 3例。对照组采用规范化癌痛治疗;观察组在规范化癌痛治疗的基础上加用龙竭散外敷疼痛处,治疗14天为1疗程,均连续治疗2疗程。观察患者疼痛控制效果、不良反应、止痛药物用量情况。结果:治疗后,2组疼痛数字评分法(NR S)评分各级评分、平均评分比较,差异均有统计学意义(P<0.05)。2组止痛药物使用量情况比较,差异有统计学意义(P<0.01)。治疗后,观察组恶心Ⅰ度2例,呕吐Ⅰ度1例;对照组恶心Ⅰ度7例,Ⅱ度1例,呕吐Ⅰ度1例。治疗后,恶心呕吐发生率观察组5.56%,对照组27.27%,2组比较,差异有统计学意义(P<0.05)。观察组Ⅱ~Ⅲ度便秘症状发生率与对照组比较,差异有统计学意义(P<0.05)。结论:龙竭散外敷能辅助治疗消化道恶性肿瘤癌性疼痛,能减少止痛药用量、减轻恶心呕吐和便秘等不良反应。

    Abstract:

    Objective:To observe the clinical effect of external application of Longjie powder on pain spots for cancer pain of digestive tract malignant tumor.M e th o d s:Divided 87 cases of patients into two groups,54 cases in the observation group and 33 cases in the control group.The control group received standardized treatment for pain,while the observation group additionally received external application of Longjie powder based on the standardized treatment for pain.The two groups continuously received treatment for two courses,fourteen days being one course.?Observed the pain control effect,adverse reactions and dosage of analgesics of patients.Results:After treatment,the comparisons of scores at all levels and the average scores in numerical rating scale(NRS)of pain between the two groups showed significance in differences(P<0.05).The comparison of the dosage of analgesics between the two groups showed significance in the difference(P<0.01).After treatment,there were two cases of nausea atⅠ degree and one case of vomiting atⅠ degree in the observation group;there were seven cases of nausea atⅠ degree and one case of vomiting atⅡ degree in the control group.After treatment,the incidence of nausea and vomiting was 5.56%in the observation group and 27.27%in the control group,differences being significant(P<0.05).The comparison of the incidence of constipation atⅡandⅢdegree between the two groups showed significance in the difference(P<0.05).Conclusion:The external application of Longjie powder has assistant therapeutic effect in treating cancer pain of digestive tract malignant tumor,which can reduce the dosage of analgesics,and relieve adverse reactions as nausea,vomiting and constipation.

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马继恒,王国方,戎云霞.龙竭散外敷治疗消化道恶性肿瘤癌性疼痛临床研究[J].新中医,2018,50(6):179-181

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  • 在线发布日期: 2018-06-05
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