Objective：To discuss the thought of syndrome differentiation of Chinese medicine and treatment rules in the treatment of autohemotherapy for chronic urticaria.Methods：Divided 120 cases of patients with chronic urticaria into different syndrome types based on the Chinese medicine syndrome differentiation.All patients were treated with autohe motherapy once a week，and ten times of treatment were one course.Recorded the urticaria activity score(UAS)in patients with different Chinese medicine syndrome types before and after treatment，and compared the clinical effect in each syndrome type group.Results：After treatment，UAS scores in the group of spleen deficiency mixed with dampness type，the group of deficiency of qiand blood type，the group of dampness-heat of intestine and stomach type，the group of wind-heat type，and the group of wind-cold type were improved at different degrees when compared with those before treatment，differences being significant( P ＜0.05， P ＜0.01).The UAS score in the group of qistagnation and blood stasis type was not significantly improved when compared with that before treatment(P ＞ 0.05).After treatment，the total clinical effective rate was 75.00%，and the highest total effective rate was 90.91%in the group of deficiency of qi and blood type.The clinical effect in each type ranked as follows：deficiency of qi and blood type＞spleen deficiency mixed with dampness type＞wind-cold type＞dampness-heat of intestine and stomach type＞wind-heat type＞qistagnation and blood stasis type.The totaleffective rate was 88.41%in patients with deficiency syndrome and was 56.86%in patients with excess syndrome，the difference being significant( P ＜0.01).Conclusion：The treatment of autohemotherapy for chronic urticaria has a better curative effect on patients with deficiency syndrome.It is more suitable to clinically apply the thought of reinforcing healthy qi and supplementing deficiency to the treatment of autohemotherapy for chronic urticaria.