Objective： To observe the clinical effe ct of modified Danggui Sini tang for urticaria of cold type.Method：Selected 70 cases of patients with urticaria of cold type as research subjects，and divided theminto the research group and the control group randomly，35 cases in each group.The research group received modified Danggui Sini tang for treatment，while the control group received the oral administration of cetirizine hydrochloride tablets.After treatment，compared and analyzed the clinicaleffect of both groups.Results：The totaleffective rate was 97.1%in the research group and 71.4%in the control group，difference being significant( P ＜0.05).Before treatment，there were no significant difference being found in the symptomscores of the two groups( P ＞ 0.05).After treatment，the symptomscores in both groups were lower than those before treatment，differences being significant( P ＜0.05)；the symptomscores in the observation group were lower than those in the control group，difference being significant( P ＜0.05).Conclusion：The clinical effect of modified Danggui Sini tang treating urticaria of cold type is better than that of the oraladministration of cetirizine hydrochloride tablets.