膈下逐瘀汤联合精准肝动脉化疗栓塞术治疗中晚期原发性肝癌临床研究
DOI:
作者:
作者单位:

作者简介:

通讯作者:

中图分类号:

R735.7

基金项目:

淅江省嘉兴市科技计划项目 (2016AY23074)


Clinical Study on Gexia Zhuyu Tang Com bined with Precise TACE for Advanced Prim ary Liver Cancer
Author:
Affiliation:

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    目的:探讨膈下逐瘀汤联合精准肝动脉化疗栓塞术(TACE)治疗原发性肝癌的临床效果。方法:将原发性肝癌患者60例随机分为2组,对照组30例予精准TACE术治疗,治疗组30例在对照组的基础上加用膈下逐瘀汤治疗,观察治疗后相关指标的变化情况。结果:治疗后2组实体瘤体积均较治疗前缩小( P <0.01);但2组间比较,差异无统计学意义( P >0.05)。实体瘤有效率治疗组为36.67%,对照组为26.67%,2组比较,差异无统计学意义( P >0.05)。治疗后2组中医症状积分均较治疗前明显改善( P <0.01),且治疗组积分改善较对照组更显著( P <0.01)。治疗后2组谷丙转氨酶(ALT)、总胆红素(TBil)、谷氨酰转肽酶(GGT)、甲胎蛋白(AFP) 值均较治疗前明显改善( P <0.01),且治疗组ALT、GGT、AFP值改善较对照组更显著( P <0.05, P <0.01)。结论:膈下逐瘀汤联合精准TACE术治疗原发性肝癌疗效肯定,可以明显改善患者临床症状、肝功能及AFP等生化指标。

    Abstract:

    Objective: To study the clinical effect of Gexia Zhuyu tang com bined with precise transcatheter arterial chemoem bolization(TACE)for advanced prim ary liver cancer.Methods:Divided 60 cases of patients with prim ary liver cancer into the two groups,30 cases in each group.The control group received precise TACE for treatment,while the treatment group additionally received Gexia Zhuyu tang based on the treatment of the control group.Observed the changes of relevant indicators after treatment.Results:The volume of solid tumor in the two groups after treatment was decreased when compared with that before treatment( P <0.01),but no significant difference was found in the comparison of the volume of solid tumor between the two groups( P >0.05).The effective rate of the solid tumor was 36.67%in the treatment group and was 26.67%in the controlgroup,there being no significance in the difference( P > 0.05).After treatment,scores of Chinese medicine syndromes in the two groups were significantly improved when compared with those before treatment( P <0.01),and the improvement in the treatment group was more obvious than that in the control group( P <0.01).After treatment,values of ALT, GGT, TBil and AFP in the two groups were significantly improved when compared with those before treatment( P <0.01),and the improvement of values of ALT,GGT and AFP in the treatment group was more obvious than that in the control group( P <0.05, P <0.01).Conclusion:The therapy of Gexia Zhuyu tang com bined with precise TACE for prim ary liver cancer has accurate curative effect, which can obviously improve clinical symptoms of patients, the liver function and some biochemical indexes including AFP.

    参考文献
    相似文献
    引证文献
引用本文

钱赟达,楼晓军,沈灵娜,陈洁,李玲.膈下逐瘀汤联合精准肝动脉化疗栓塞术治疗中晚期原发性肝癌临床研究[J].新中医,2018,50(9):140-143

复制
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期: 2018-09-04
  • 出版日期: