八珍益母胶囊联合小剂量米非司酮治疗气滞血瘀型子宫腺肌症临床研究
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R711.71

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海宁市科技计划项目 (2017188)


Clinical Study on Bazhen Yimu Capsules Combined with Low-dose Mifepristone for Adenomyosis of Qi Stagnation and Blood Stasis Type
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    摘要:

    目的:观察八珍益母胶囊联合小剂量米非司酮治疗气滞血瘀型子宫腺肌症的临床疗效。方法:将140例气滞血瘀型子宫腺肌症患者随机分为2组各70例。对照组给予非司酮片内服治疗,观察组给予八珍益母胶囊联合小剂量米非司酮内服治疗。评估2组临床疗效,观察患者治疗前后相关指标的变化。结果:观察组总有效率为92.86%,高于对照组71.43%,差异有统计学意义(P<0.05)。与治疗前比较,观察组和对照组痛经症状积分均低于治疗前(P<0.05)。观察组治疗后改善程度大于对照组(P<0.01)。观察组气滞血瘀证候疗效总有效率为94.52%,高于对照组31.50%,差异有统计学意义(P<0.05)。与治疗前比较,2组子宫体积均低于治疗前(P<0.05)。2组间相比较,观察组的子宫体积减小程度的差值大于对照组(P<0.05)。与治疗前比较,2组腺肌瘤大小均低于治疗前(P<0.05)。2组间比较,观察组腺肌瘤大小减小程度大于对照组(P<0.05)。结论:八珍益母胶囊联合小剂量米非司酮治疗气滞血瘀型子宫腺肌症效果显著,能更有效改善气滞血瘀证证候、痛经程度。

    Abstract:

    To observe the clinical effect of Bazhen Yimu capsules combined with low-dose mifepristone for adenomyosis of qi stagnation and blood stasis type.Methods:A total of 140 cases of patients with adenomyosis of qi stagnation and blood stasis type were randomly divided into two groups,70 cases in each group.The control group was treated with mifepristone tablets orally,and the observation group was treated with Bazhen Yimu capsules combined with low-dose mifepristone orally.The clinical effect in the two groups was evaluated,and the changes in the related indexes before and after treatment were observed.Results:The total effective rate was 92.86%in the observation group,higher than that of 71.43%in the control group,the difference being significant(P < 0.05).After treatment,the scores of dysmenorrhea in the two groups were lower than those before treatment(P < 0.05).After treatment,the degree of improvement in the observation group was larger than that in the control group(P<0.01).The total effective rate of syndrome of qi stagnation and blood stasis was 94.52%in the observation group,higher than that of 31.50%in the control group,the difference being significant(P<0.05).After treatment,the uterine volumes in the two groups were smaller than those before treatment(P<0.05).The reduction of the uterine volume in the observation group was larger than that in the control group(P<0.05).After treatment,the sizes of adenomyoma in the two groups were smaller than those in the control group(P < 0.05).The reduction of the size of adenomyoma in the observation group was larger than that in the control group(P<0.05).Conclusion:The therapy of Bazhen Yimu capsules combined with low-dose mifepristone in treating adenomyosis of qi stagnation and blood stasis type has significant curative effect,which can more effectively reduce the syndrome of qi stagnation and blood stasis and degree of dysmenorrhea.

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孙铮,李莎,何新琴.八珍益母胶囊联合小剂量米非司酮治疗气滞血瘀型子宫腺肌症临床研究[J].新中医,2019,51(10):176-178

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  • 在线发布日期: 2019-10-11
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