To observe the clinical effect of Wenshen Haoxue tang combined with mifepristone for endometriosis of kidney deficiency and blood stasis type.Methods：Selected 82 cases of patients with endometriosis of kidney deficiency and blood stasis type and divided them into the observation group and the control group according to the random number table，41 cases in each group.Both groups received the treatment with mifepristone，while the observation group additionally received the application of Wenshen Huoxue tang.Compared the clinical effect of the two groups，observed the changes of symptom scores，sex hormones and inflammatory factor levels before and after treatment in the two groups；recorded the occurrence of adverse reactions.Results：The total effective rate was 87.80%in the observation group and 68.29%in the control group，compared the two groups，difference being significant(P ＜ 0.05).After treatment，the scores of lower abdominal pain during menstruation，dizziness and tinnitus and pelvic nodal masses in the two groups were reduced when compared with those before treatment，and the scores of the three symptoms mentioned above in the observation group were lower than those in the control group，difference being significant(P ＜ 0.05).After treatment，the levels of estradiol(E2)，follicle-stimulating hormone(FSH)， luteinizing hormone(LH)， tumor necrosis factor-α (TNF-α)and transforming growth factor-β1(TGF-β1)in the two groups were all reduced when compared with those before treatment(P＜0.05).And the decrease of levels of the three sex hormones and two inflammatory factors mentioned in the observation group were significantly obvious than that in the control group(P＜0.05).The incidence of adverse reactions was 14.63%in the observation group and 9.76%in the control group，difference being insignificant when compared the two groups(P ＞ 0.05).Conclusion：The application of Wenshen Huoxue tang combined with mifepristone for endometriosis of kidney deficiency and blood stasis type is safe and effective.It can improve the symptoms of patients and regulate the levels of sex hormones and inflammatory factors.