羚角五虎汤联合磷酸奥司他韦颗粒治疗儿童流行性感冒临床研究
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R725.1

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Clinical Study on Lingjiao Wuhu Tang Combined with Oseltamivir Phosphate Granules in Treating Influenza in Children
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    摘要:

    目的:观察羚角五虎汤联合磷酸奥司他韦颗粒治疗儿童流行性感冒的疗效。方法:纳入156例热毒袭肺型流行性感冒患儿作为研究对象,随机分成2组各78例,2组均以磷酸奥司他韦颗粒治疗,观察组联合羚角五虎汤治疗。2组均治疗5天。记录2组患儿的症状缓解时间,治疗前后评定中医证候积分,比较2组的临床疗效。结果:治疗后,观察组总有效率为93.59%,高于对照组的80.77%,2组比较,差异有统计学意义(P<0.05)。观察组退热时间、鼻塞消失时间、咳嗽消失时间均较对照组缩短,差异均有统计学意义(P<0.01)。2组中医证候积分均较治疗前下降(P<0.01),观察组中医证候积分低于对照组(P<0.01)。2组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:羚角五虎汤联合磷酸奥司他韦颗粒治疗儿童流行性感冒能够缩短症状缓解时间,提高疗效。

    Abstract:

    To observe the curative effect of Lingjiao Wuhu tang combined with oseltamivir phosphate granules in treating influenza in children.Methods:A total of 156 cases of children with influenza of heat-toxicity attacking lung type were divided into two groups randomly,78 cases in each group.Both groups were treated with oseltamivir phosphate granules and the observation group was additionally treated with Lingjiao Wuhu tang.Both groups were treated for five days.The symptom relief time of children in the two groups was recorded,the Chinese medicine syndrome scores were evaluated before and after treatment,and the clinical effect in both groups was compared.Results:After treatment,the total effective rate was 93.59%in the observation group,higher than that of 80.77%in the control group,the difference being significant(P< 0.05).The disappearance time of fever,nasal obstruction and cough in the observation group was shorter than that in the control group,differences being significant(P<0.01).Chinese medicine syndrome scores in both groups were decreased when compared with those before treatment(P < 0.01),and those in the observation group were lower than those in the control group(P<0.01).There was no significant difference in the comparison of the incidence of adverse reactions between the two groups(P>0.05).Conclusion:The therapy of Lingjiao Wuhu tang combined with oseltamivir phosphate granules in treating influenza in children,can shorten the relief time of symptoms and improve curative effect.

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龚丹凤.羚角五虎汤联合磷酸奥司他韦颗粒治疗儿童流行性感冒临床研究[J].新中医,2019,51(10):197-199

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  • 在线发布日期: 2019-10-11
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