茵栀黄颗粒联合双歧三联活菌冲剂治疗新生儿黄疸临床研究
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R722.17

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浙江省2017年度县级科技计划项目 (医学类)( 2017SK08)


Clinical Study on Yinzhihuang Granules Combined with Bifidobacterium Triple Viable Powder in Treating Neonatal Jaundice
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    摘要:

    目的:观察茵栀黄颗粒联合双歧三联活菌冲剂治疗新生儿黄疸的临床疗效。方法:将600例新生儿黄疸患儿按照随机数字法分为试验组和对照组各300例。对照组采用一般治疗,试验组在对照组基础上给予茵栀黄颗粒联合双歧三联活菌冲剂治疗。比较2组患儿治疗前和治疗后第2、4、6天经皮胆红素值的变化情况;比较2组患儿胎粪转黄的时间;比较2组患儿在治疗中的不良反应发生率。结果:治疗前,2组患儿的经皮胆红素值比较,差异无统计学意义(P>0.05)。治疗后,2组患儿的经皮胆红素值均逐渐下降;治疗后第2天,2组患儿经皮胆红素值比较,差异无统计学意义(P>0.05);在治疗后第4、6天,试验组患儿的经皮胆红素值低于对照组,差异有统计学意义(P<0.05)。试验组患儿胎粪转黄的时间早于对照组,差异有统计学意义(P<0.05)。试验组不良反应发生率为3.33%,对照组不良反应发生率为2.67%,2组比较,差异无统计学意义(P>0.05)。结论:茵栀黄颗粒联合双歧三联活菌冲剂治疗新生儿黄疸,疗效肯定,安全可靠。

    Abstract:

    To observe the clinical effect of the therapy of Yinzhihuang granules combined with Bifidobacterium Triple Viable powder in treating neonatal jaundice.Methods:A total of 600 cases of babies with neonatal jaundice were divided into the experiment group and the control group according to random number table method,300 cases in each group.The control group was treated with conventional treatment,and the experiment group was treated with Yinzhihuang granules combined with Bifidobacterium Triple Viable powder based on the treatment of the control group.The changes of percutaneous bilirubin before treatment and on the 2nd,4thand 6thdays after treatment,the time of meconium yellowing,and the incidence of adverse reactions was compared between the two groups.Results:Before treatment,there was no statistically significant difference in the comparison of the level of percutaneous bilirubin between the two groups(P > 0.05).After treatment,the level of percutaneous bilirubin in both groups were decreased gradually; on the 2ndday after treatment, there was no statistically significant difference in the comparison of the level of percutaneous bilirubin between the two groups(P>0.05).On the 4thand 6thdays after treatment,the level of percutaneous bilirubin in the experiment group was lower than that in the control group,the difference being significant(P<0.05).The time of meconium yellowing in the experiment group was earlier than that in the control group,the difference being significant(P<0.05).The incidence of adverse reactions was 3.33%in the experiment group and 2.67%in the control group,there being no significant difference between the two groups(P>0.05).Conclusion:The therapy of Yinzhihuang granules combined with Bifidobacterium Triple Viable powder has significant therapeutic effect in treating neonatal jaundice and is safe and reliable.

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戴丽凤,章樱,李洁,姚露军.茵栀黄颗粒联合双歧三联活菌冲剂治疗新生儿黄疸临床研究[J].新中医,2019,51(10):208-210

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  • 在线发布日期: 2019-10-11
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