银黄清肺胶囊辅助治疗重症肺炎痰热壅肺证临床研究
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Clinical Study on Yinhuang Qingfei Capsules for Severe Pneumonia with Phlegm-heat Obstructing the Lung Syndrome
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    摘要:

    目的:观察银黄清肺胶囊辅助治疗重症肺炎痰热壅肺证的临床疗效。方法:选取80例重症肺炎痰热壅肺证患者,按照随机数字表法分为治疗组和对照组各40例。2组均予常规西医治疗,对照组给予注射用亚胺培南西司他丁钠静脉滴注,治疗组在对照组基础上予银黄清肺胶囊口服。连续治疗2 周后,比较2 组动脉血气指标、急性生理和慢性健康状况评分Ⅱ(APACHE Ⅱ)、临床肺部感染评分(CPIS) 及临床疗效。结果:治疗后,2组二氧化碳分压(PaCO2) 水平明显降低(P<0.01),血氧饱和度(SaO2) 及血氧分压(PaO2) 水平显著升高(P<0.01);治疗组PaCO2、SaO2及PaO2水平改善均优于对照组,差异有统计学意义(P<0.01)。治疗后,2 组APACHEⅡ及CPIS 评分显著降低(P<0.01);且治疗组APACHEⅡ及CPIS 评分显著低于对照组(P<0.01)。治疗组总有效率为95.0%,明显高于对照组的77.5%(P<0.05)。结论:在常规西医治疗基础上加用银黄清肺胶囊辅助治疗重症肺炎痰热壅肺证,可有效改善患者的症状体征,控制感染,提高临床疗效。

    Abstract:

    Abstract: Objective: To observe the clinical effect of Yinhuang Qingfei capsules in adjuvant treatment for severe pneumonia with phlegm-heat obstructing the lung syndrome. Methods : A total of 80 cases of patients with severe pneumonia with phlegm-heat obstructing the lung syndrome were divided into the treatment group and the control group,40 cases in each group. Both groups were given routine western medicine treatment;the control group was additionally treated with imipenem and cilastatin sodilum for injection by intravenous drip, and the treatment group was additionally given oral administration of Yinhuang Qingfei capsules based on the treatment of the control group. After two- week treatment, the blood gas indexes of arteries, the scores of the Acute Physiology and Chronic Health Evaluation Ⅱ(APACHE Ⅱ) and the Clinical Pulmonary Infection Score(CPIS) as well as the clinical effect were compared between the two groups. Results:After treatment,the levels of partial pressure of carbon dioxide(PaCO2) in the two groups were significantly decreased(P<0.01),and the levels of oxygen saturation(SaO2) and partial pressure of oxygen(PaO2) were significantly increased(P<0.01); The improvement of PaCO2,SaO2 and PaO2 in the treatment group was more than that in the control group,differences being significant(P<0.01). After treatment,the scores of APACHE Ⅱ and CPIS in the two groups were significantly decreased(P<0.01),and the above two scores in the treatment group were significantly lower than those in the control group(P<0.01). The total effective rate was 95.0% in the treatment group,significantly higher than that of 77.5% in the control group(P<0.05).Conclusion:Based on routine rehabilitation measures,the adjuvant treatment of Yinhuang Qingfei capsules for patients with severe pneumonia with phlegm- heat obstructing the lung syndrome can effectively improve their symptoms, signs and clinical effect,and control infection.

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张浙东,毛晶晶.银黄清肺胶囊辅助治疗重症肺炎痰热壅肺证临床研究[J].新中医,2020,52(10):47-49

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  • 在线发布日期: 2020-05-26
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