Objective： To systematically evaluate the clinical effect and safety of Shegan Mahuang tang treating refractory asthma.Methods：Databases such as the Cochrane Library，EMBASE，PubMed，Chinese Periodical Full-Text Database(CNKI)，Chinese Sci-Tech Periodical Full-Text Database(VIP)，and Wanfang Database(wanfang)were selected for the analysis.Literature of randomized controlled trials in treating refractory asthma with Shegan Mahuang tang was retrieved from the time of database establishment to September，2017 on the computer.References included in the study were searched as well.Two researchers were responsible for the screening of retrieved literature as well as the extraction of valid data.The meta-analysis was eventually conducted via RevMan software.Results：Eight randomized clinical controlled trials including 563 cases of patients were brought into the meta-analysis.Results showed that the additional application of Shegan Mahuang tang based on western medicine，compared with the simple application of western medicine therapy，could increase the total effective rate and the forced expiratory volume in one second(FEV1)of clinical patients，and could improve asthma control test scores of patients，differences being significant.Conclusion：Shegan Mahuang tang can improve the total effective rate，FEV1and asthma control testscores ofpatients.Nevertheless，with the limitation of the quantity and quality of the studies being included in the analysis，the results still need to be further verified by a stricter，multicenter and large-sampled randomized double-blind trial.