小儿反复呼吸道感染中医体质类型分布的系统评价
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R725.6

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Systematic Review of Distribution of Chinese Medicine Constitution Types of Repeated Respiratory Infections in Children
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    摘要:

    目的:分析小儿反复呼吸道感染(RRTI)中医体质类型的分布情况,探讨小儿反复呼吸道感染的中医体质分布规律。方法:检索中国知网、维普、万方数据、PubMed等数据库,纳入所有小儿反复呼吸道感染中医体质类型的临床研究文献。采用Stata12.0软件进行单组率的Meta分析,并以百分率及其95%可信区间表达效应值。结果:共纳入7项病例对照研究和8项横断面研究,共2095例患儿。经Meta分析,结果显示平和质在反复呼吸道感染患儿中的比例为0.31[95%CI(0.15,0.48), P <0.000 1];气虚质在反复呼吸道感染患儿中的比例为0.47[95%CI(0.28,0.67), P <0.000 1];阴虚质在反复呼吸道感染患儿中的比例为0.36[95%CI(0.21,0.51), P <0.0001];湿热质在反复呼吸道感染患儿中的比例为0.24[95%CI(0.14,0.35),P <0.000 1]。纳入的资料中有7项病例对照研究的方法学质量相对较高,8项横断面研究的方法学质量较低,总体存在一定的偏倚风险。结论:气虚质、阴虚质、湿热质是反复呼吸道感染患儿的主要偏颇体质类型;受纳入原始文献数量和质量等因素所限,上述结论可能存在一定的偏倚风险。

    Abstract:

    Objective: To investigate the distribution regularity of Chinese medicine constitution by analyzing the distribution of Chinese medicine constitution types of repeated respiratory infections in children.Methods:Retrieved databases of China National Knowledge Infrastructure,VIP,Wanfang data and Pub Med,and incorporated all clinical research literature on the Chinese medicine constitution types of repeated respiratory infections in children.Applied Stata12.0 software to performmeta-analysis of single-group rate,and expressed the effect value based on the rate and its 95%confidence interval.Results:There was a total of 2,095 children with seven case-control studies and eight cross-sectional studies included.Meta-analysis showed that the proportion of yin-yang harmony constitution in children with repeated respiratory infections was 0.31[95% CI(0.15,0.48),P < 0.000 1];the proportion of qi-deficiency constitution in children with repeated respiratory infections was 0.47[95%CI(0.28,0.67),P < 0.000 1];the proportion of yin-deficiency constitution in children with repeated respiratory infections was 0.36[95%CI(0.21,0.51),P < 0.000 1];the proportion of damp-heat constitution in children with repeated respiratory infections was 0.24[95% CI(0.14,0.35),P < 0.000 1].The methodological quality of the seven case-control studies was relatively high,while that of the eight cross-sectional studies was low,and there was overall a certain risk of bias.Conclusion:Qi-deficiency constitution,yin-deficiency constitution and damp-heat constitution are the main types of bias constitution of children with repeated respiratory infections.Limited by the number and quality of the original literature,the conclusion mentioned above may have a certain risk of bias.

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朱英姿.小儿反复呼吸道感染中医体质类型分布的系统评价[J].新中医,2018,50(7):34-38

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  • 在线发布日期: 2018-09-21
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