益胃消癌汤辅助化疗治疗进展期胃癌临床研究
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R735.2

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Clinical Study on Yiwei Xiaoai Tang Adjuvant Chemotherapy for Advanced Gastric Cancer
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    摘要:

    目的:观察益胃消癌汤辅助化疗治疗进展期胃癌的临床疗效。方法:选取120 例进展期胃癌患者,采用随机数字表法分为观察组和对照组各60 例。对照组采用化疗方案治疗,观察组在对照组基础上给予益胃消癌汤治疗。比较2 组治疗前后中医证候评分、红细胞计数、白细胞计数及癌胚抗原水平,并评价临床疗效。结果:观察组总有效率为93.33%,高于对照组80.00%,差异有统计学意义(P<0.05)。治疗前,2 组红细胞计数、白细胞计数、癌胚抗原水平比较,差异无统计学意义(P>0.05)。治疗后,2 组红细胞计数、白细胞计数、癌胚抗原水平较治疗前降低(P<0.05),但观察组红细胞计数、白细胞计数均高于对照组,癌胚抗原水平低于对照组(P<0.05)。治疗前,2 组胃脘疼痛、食欲不振、早饱、上腹胀评分比较,差异无统计学意义(P>0.05)。治疗后,2 组胃脘疼痛、食欲不振、早饱、上腹胀评分较治疗前降低,且观察组胃脘疼痛、食欲不振、早饱、上腹胀评分均低于对照组,差异有统计学意义(P<0.05)。结论:益胃消癌汤辅助化疗治疗进展期胃癌具有良好的临床疗效,能减轻患者临床症状,降低癌胚抗原水平,改善血常规指标。

    Abstract:

    Abstract: Objective: To observe the clinical effect of Yiwei Xiaoai tang adjuvant chemotherapy on advanced gastric cancer. Methods:A total of 120 patients with advanced gastric cancer were selected and divided into the observation group and the control group by random number table method, with 60 cases in each group. The control group was treated with chemotherapy,and the observation group was additionally treated with Yiwei Xiaoai tang. The Chinese medicine syndrome scores,RBC count,WBC count and levels of carcinoembryonic antigen were compared between the two groups before and after treatment, and the clinical effects were evaluated. Results: The total effective rate was 93.33% in the observation group,higher than that of 80.00% in the control group,the difference being significant(P<0.05). Before treatment,there was no significant difference in the RBC count,the WBC count and the level of carcinoembryonic antigen between the two groups(P>0.05). After treatment, the RBC count, WBC count and the levels of carcinoembryonic antigen in both groups were decreased when compared with those before treatment(P<0.05), but the RBC count and the WBC count in the observation group were higher than those in the control group,and the level of carcinoembryonic antigen was lower(P<0.05). Before treatment,there was no significant difference in the scores of gastric cavity pain,poor appetite,early satiety and upper abdominal distension between the two groups(P>0.05). After treatment, the scores of gastric cavity pain, poor appetite, early satiety and upper abdominal distension in both groups were decreased when compared with those before treatment,and the above scores in the observation group were lower than those in the control group,the difference being significant(P<0.05). Conclusion: Yiwei Xiaoai tang adjuvant chemotherapy has a great clinical effect on the treatment of advanced gastric cancer,which can lessen the clinical symptoms of patients,reduce the level of carcinoembryonic antigen and improve the blood routine indexes.

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王耀辉,付巧梅.益胃消癌汤辅助化疗治疗进展期胃癌临床研究[J].新中医,2022,54(9):148-151

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  • 在线发布日期: 2022-05-09
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