Abstract： Professor CUI Yun holds that the exhaustion of the tenth heavenly stem and the kidney failure is the fundamental pathogenesis of male climacteric syndrome， and water failing to nourish wood and binding constraint of liver qi are the core pathogenesis，therefore，both physiological and psychological diagnosis and treatment should be emphasized. The treatments for the body include supplementing the liver and kidney to resolve deficiency and consumption， and nourishing the kidney， soothing the liver and eliminating pathogen to regulate qi and blood； the chosen of prescription and medication should be accurate and appropriate. As for the mind，it is mainly to regulate emotions through verbal persuasion and decompressive exercises.