Abstract：Objective：To observe the clinical effect of method of tonifying kidney，activating blood and regulating menstrual cycle combined with Chinese medicine packages on intrauterine adhesions (IUA)，and its effect on platelet-derived growth factor (PDGF-BB)，transforming growth factor-β1 (TGF-β1) and basic fibroblast growth factor (bFGF). Methods：A total of 40 cases of IUA patients who underwent hysteroscopic separation of uterine adhesions were divided into the control group (treated with method of tonifying kidney， activating blood and regulating menstrual cycle) and the trial group (treated with method of tonifying kidney， activating blood and regulating menstrual cycle combined with Chinese medicine packages) according to random number table method，with 20 cases in each group. Both groups were treated for three menstrual cycles and followed up for one year. Clinical effects， endometrial thickness， uterine artery blood flow parameters [pulse index (PI) and resistance index (RI)]，levels of PDGF-BB，TGF-β1 and bFGF in serum， incidence of uterine readhesion，and pengnancy were compared between the two groups. Results：After treatment，the total effective rate was 85.00% in the trial group，higher than that of 55.00% in the control group (P＜0.05). Endometrial thickness in the two groups was increased when compared with that before treatment (P＜0.05)，and PI and RI were decreased when compared with those before treatment (P＜0.05). The endometrial thickness in the trial group was higher than that in the control group (P＜0.05)，and PI and RI were lower than those in the control group (P＜0.05). The levels of PDGF-BB， TGF- β1 and bFGF in serum in the two groups were decreased when compared with those before treatment (P＜0.05)，and the levels of PDGF-BB， TGF- β1 and bFGF in serum in the trial group were lower than those in the control group (P＜0.05). After three months of follow-up， the incidence of readhesion was 5.88% in the trial group，lower than that of 27.27% in the control group (P＜0.05). Following up for one year，the pregnancy rate was 40.00% in the trial group，higher than that of 5.00% in the control group (P＜0.05). Conclusion： The method of tonifying kidney， activating blood and regulating menstrual cycle combined with Chinese medicine packages for IUA can increase endometrial thickness， improve uterine artery blood flow and clinical symptoms， effectively regulate the levels of PDGF-BB， TGF- β1 and bFGF， reduce the occurrence of uterine readhesion，and increase the pregnancy rate.