Objective：To intervene the salivary secretion of healthy people with self-made lemon spray and Wumei spray，and to observe the effect of the two sprays on the physiological function and biochemical indexes of salivary gland.Methods：Collected saliva from 42 college volunteers，adopted self-control study method to divide them into basal saliva group，lemon spray group and Wumei spray group.Compared the exponential function of saliva flow rate，pH，salivary amylase，Na+，K+，and Na+/K+ratio among the three groups.Results：The exponential function of saliva flow rate of Wumei spray group was higher than that of basal saliva group(P＜0.05).The pH value of lemon spray group was higher than that of both Wumei spray group and basal saliva group(P＜0.01).Concentrations of amylase，Na+and K+of both lemon spray group and Wumei spray group were all lower than those of basal saliva group(P＜0.01).The concentrations of K+of lemon spray group were lower than those of Wumei spray group(P＜0.01)，and Na+/K+ratio of lemon spray group was lower than that of basalsaliva group(P＜0.01).Conclusion：The effect of stimulating salivary secretion of the Wumei spray is more significant than that of lemon spray，while lemon spray plays a protective role in adjusting the pH value of oralcavity.