Objective：To observe the clinical effect of fumigation and washing with Jianghuang san for newborns with neonatal jaundice of damp-heat stagnation and steaming type.Methods：Selected 96 cases of newborns with neonatal jaundice of damp-heat stagnation and steaming type as study objects，and divided them into the control group and the treatment group randomly，48 cases in each group.Both groups receivedYinzhihuang particles and live binary bacillus subtilis orally，while the treatment group additionally received fumigation and washing with Jianghuang san.Evaluated the clinical effect according to the remission of each symptom in newborns after treatment，detected changes of serum bilirubin level before and after treatment，and recorded the regression time of jaundice.Results：The total effective rate was 62.5%in the control group and was 89.6%in the treatment group，the difference being significant(P＜0.01).Before treatment，the serum bilirubin levels of the two groups were compared，there being no significance in differences(P＞0.05).After three and five days of treatment as well as ten days of follow-up，the serum bilirubin levels of two groups were both lower than those before treatment(P＜0.05).On the third day of treatment，the serum bilirubin levels of the two groups were compared，there being no significance in differences(P＞0.05).On the fifth day of treatment and the tenth day of follow-up，the serum bilirubin levels of the treatment group were lower than those of the control group(P＜0.05).After treatment，the regression time of jaundice in the treatment group was shorter than that in the control group(P＜0.05).The incidence of adverse reaction in the control group was 6.3%and was 10.4%in the treatment group，there being no significance in the difference(P＞0.05).Conclusion：The additional application of Jianghuang san based on the oral administration of Yinzhihuang particles and live binary Bacillus subtilis has significant effect for the treatment of neonatal jaundice of damp-heat stagnation and steaming type.With high safety，it can effectively reduce serum bilirubin levels of jaundice in the newborns and promote the regressionof jaundice.