Objective：To observe the short-term and long-term clinical effect of integrated Chinese and western medicine therapy for chronic rhinitis.Methods：Divided 150 cases of patients with chronic rhinitis in department of otolaryngology in Xinyang Third People’s Hospital into two groups randomly，75 cases in each group.Both groups receivedbudesonide nasal spray and clarithromycin for treatment，while the observation group additionally received rhinitis prescription by oral administration and point massage.The overall treatment for both groups lasted for 4 weeks.The short-term and long-term clinical effect of both groups was evaluated according to improvements of clinical symptoms.Nasal resistance of patients before and after treatment were measured by nasal resistance instrument.Adverse reaction of patients in both groups during the treatment were recorded.Results：The short-term total effective rate was 65.33%in the observation group and 61.33%in the control group，there being no significance in the difference(P＞0.05).The long-term total effective rate was 86.67%in the observation group and 70.67%in the control group，the difference being significant(P＜0.05).Compared with the short-term curative effect，the total effective rate in the control group was increased，there being no significance in the difference(P＞0.05)；long-term curative effect in the observation group was better than the short-term curative effect，the difference being significant(P ＜ 0.05).After treatment，nasal resistance levels in both groups were decreased significantly，differences being significant(P＜0.05).Nasal resistance levels in the observation group were decreased more significantly than those in the control group，the difference being significant(P＜0.05).No significant difference was found in the comparison of safety and the incidence rate of adverse reaction of patients between the two groups(P＞0.05).Conclusion：Integrated Chinese and western medicine therapy for chronic rhinitis can effectively relief clinical symptoms and signs such as nasal obstruction and nasal discharge as wellas improve nasalventilation of patients，which has significant clinicaleffect and safety.