Objective：To observe the clinical effect of Shufeng Qingre Jiedu prescription for chronic obstructive pulmonary disease(COPD)in acute exacerbation of wind-heat attacking lung type.Methods：Selected 90 cases of patients with COPD in acute exacerbation of wind-heat attacking lung type，and divided them randomly into the control group and the observation group，45 cases in each group.The control group was given continuous low-flow oxygen，maintaining the balance of water and electrolyte， anti-inflammatory and antiasthmatic， resolving phlegm and relieving cough and other symptomatic treatments.The observation group was additionally given Shufeng Qingre Jiedu prescription based on treatment of the control group.Both groups receivedcontinuous treatment for 2 weeks.Observed clinical curative effect and changes of indexes of lung function which includes forced expiratory volume at the first second(FEV1)，forced vital capacity(FVC)and value of FEV1/FVC and the changes of index of arterial blood gas analysis which includes partial pressure of Oxygen(PaO2)and partial pressure of carbon dioxide(PaCO2)in both groups before and after treatment.Results：The total curative rate was 93.33%in the observation group and was 75.56%in the control group，the difference being significant(P＜ 0.05).After treatment，levels of FVC，FEV1and FEV1/FVC in both groups were higher than those before treatment(P＜0.05).Levels of FVC，FEV1and FEV1/FVC in the observation group were higher than those in the control group(P＜ 0.05).After treatment，PaO2levels in both groups were increased when compared with those before treatment(P＜0.05)，while PaCO2levels were decreased(P＜ 0.05).PaO2levels in the observation group were higher than those in the control group(P＜ 0.05)，while PaCO2levels were lower(P＜0.05).Conclusion：Based on the routine treatment，additional application of Shufeng Qingre Jiedu prescription can improve the clinical effect，lung functionand index of arterial blood gas analysis of COPD patients in acute exacerbation of wind-heatattacking lung type.