Objective： To observe and evaluate the clinical effect of Gubing Huoxue ointment in treating femoral head necrosis.Methods：Selected 100 cases of patients with osteonecrosis of the femeral head admitted into the department of orthopaedics and traumatology in our hospital，and divided them into two groups randomly，50 cases in each group.The observation group receivedthe treatment of external application of Gubing Huoxue ointment combined with joint function exercise as well as skin traction on both lower extremities；the control group received the treatment of oral application of compound tablets of red-rooted salvia combined with the joint function exercise as well as skin traction on both lower extremities.Observed and recorded in both groups the total effective rate，quantitative Chinese medicine syndrome scores，visual analogue scale(VAS)，Harris scores and SF-36 scale for evaluating the function of hip joint and life quality before and after treatment.Results：After treatment，Harris scores and SF-36 scores in both groups were higher than those before treatment，while VAS scores were lower than those before treatment，differences being significant(P＜ 0.05).Harris scores and SF-36 scores in the observation group were both higher than those in the control group，while VAS scores were lower than those in the control group，differences being significant(P＜ 0.05).After treatment，quantitative syndrome scores of pain，claudication，X ray，and summing scores in the two groups were respectively compared with those before treatment，differences being significant(P＜0.05).Quantitative syndrome scores of pain，claudication and summing scores in the observation group was compared with that in the control group，differences being significant(P＜0.05).The total effective rate in the observation group was 82.0%，being higher than 70.0%in the control group.Conclusion：External application of Gubing Huoxue ointment for osteonecrosis of the femeral head can effectively release the clinical syndromes of patients and improve life quality with significant clinical effect，which is worth being applied in clinical practice.