Objective： To explore the administration rule of Chinese medicine in treating menopausal arthritis.Methods：China National Knowledge Infrastructure(CNKI)，Chinese Biological Medical Disc(CBM)， PubMed， and other databases were searched to collect related literature about the differentiation and treatment of menopausal arthritis.Symptomsand prescriptions were extracted to establish a database with cases of menopausal arthritis.Data mining methods such as fre-quency analysis，latent structure models，and frequent itemset were employed to analyze the administration rule of Chinese medicine in treating menopausal arthritis.Results：A total of 604 medical cases were selected into the study and 16 cases of high frequency symptoms were found in the medical cases.A latent structure model of menopausal arthritis syndrome was established.There were respectively 8 kinds being found in high frequency prescriptions，treatment and medicine， mining symptoms-flavour of medicine， and frequent itemset of flavour of medicine combination.Conclusion： The treatment of Chinese medicine for menopausal arthritis is mostly based on methods such as tonifying qi，blood，liver and kidney， as well as dispelling cold and removing dampness.Commonly used Chinese medicine prescriptions for the disease include Buzhong Guizhi tang，Erxian tang and Honghua Taoren tang.Both the aforesaid methods and prescriptions can provide references for the clinical treatment of menopausal arthritis.