ObjectiveTo observe the effect of Ankun Zhongzipills on antral follicle count(AFC)and ovarian volume in patients of diminished ovarian reserve(DOR)with kidney deficiency syndrome.MethodsSelected 200 cases of DOR patients with kidney deficiency syndrome as study subjects，and divided them into the treatment group and the control group according to the random number table method，100 cases in each group.The treatment group was given oral application of Ankun Zhongzi pills，while the control group receivedhormone replacement therapy for treatment.The treatment of the two groups both continuously lasted for 3 menstrual cycles.Recorded kidney deficiency syndrome scores of patients before and after treatment，and detected AFC and ovarian volume of patients before and after treatment.ResultsAfter one month of treatment，kidney deficiency syndrome scores in both groups were lower than those before treatment(P＜0.01)，there was no significant difference being found in the intergroup comparison(P＞0.05).Kidney deficiency syndrome scores detected after two months of treatment in both groups were lower than those after one month of treatment(P＜0.01).The syndrome scores detected after three months of treatment in both groups were lower than those after two months of treatment(P ＜ 0.01)，and the syndrome scores in the treatment group were lower than those in the control group in the same period(P＜0.01).After treatment，AFC in the two groups was both increased when compared with that before treatment(P ＜ 0.01)，and AFC in the treatment group was higher than that in the control group(P＜0.01)，the differences being significant(P＜0.01).After treatment，ovarian volume of both right side and left side was increased when compared to that before treatment(P ＜ 0.01)，and ovarian volume of both right side and left side of the treatment group was larger than that of the control group(P＜0.01).ConclusionThe therapy of Ankun Zhongzi pills can effectively improve symptoms of DOR patients with kidney deficiency syndrome，increase antral follicle count and enlarge the ovarian volume，as well as improve the ovarian function.