槐杞黄颗粒联合醋酸泼尼松片治疗气阴两虚型小儿肾病综合征临床观察
DOI:
作者:
作者单位:

作者简介:

通讯作者:

中图分类号:

R726.9

基金项目:


Clinical Observation of Huaiqihuang Granules Combined with Prednisone Acetate Tablets for Children Nephrotic Syndrome of Qi-yin Deficiency Type
Author:
Affiliation:

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    目的:观察槐杞黄颗粒联合醋酸泼尼松片治疗气阴两虚型小儿肾病综合征的临床疗效。方法:选取70例气阴两虚型肾病综合征患儿,随机分为对照组与观察组各35例。对照组采用醋酸泼尼松片治疗,观察组在对照组用药基础上加用槐杞黄颗粒,2组均治疗4周。治疗后评估治疗效果,观察患儿治疗前后各项免疫功能指标的变化情况。结果:观察组治疗总有效率94.29%,对照组治疗总有效率77.14%,2组比较,差异有统计学意义(P<0.05)。治疗后,观察组IgG及IgA水平均较治疗前升高,且均高于同期对照组,差异均有统计学意义(P<0.05);对照组IgG、IgA及IgM水平及观察组lgM水平与治疗前比较,差异均无统计学意义(P>0.05)。治疗后,观察组CD4+水平及CD4+/CD8+值均较治疗前上升,且均高于同期对照组,差异均有统计学意义(P<0.05);2组CD8+水平、对照组CD4+水平及CD4+/CD8+值与治疗前比较,差异均无统计学意义(P>0.05)。结论:槐杞黄颗粒联合醋酸泼尼松片治疗气阴两虚型小儿肾病综合征,能有效缓解患儿的临床症状,改善免疫功能,效果显著。

    Abstract:

    Objective:To observe the clinical effect of Huaiqihuang granules combined with prednisone acetate tablets for children nephrotic syndrome of qi-yin deficiency type.MethodsDivided 70 cases of children with nephrotic syndrome of qi-yin deficiency type into the control group and the observation group randomly,35 cases in each group.Both groups receivedprednisone acetate tablets for treatment,while the observation group additionally received Huaiqihuang granules.Both groups received treatment for 4 weeks.After treatment,evaluated the curative effect and observed changes of all indexes of immune function before and after treatment of children in both groups.ResultsThe total effective rate was 94.29% in the observation group and was 77.14% in the control group,the difference being significant(P<0.05).After treatment,levels of IgG and IgA in the observation group were increased when compared with those before treatment and higher than those in the control group in the same period,differences being significant(P<0.05).Compared levels of IgG,IgA and IgM in the control group and IgM levels in the observation group before and after treatment,there was no significance in differences(P>0.05).After treatment,CD4+levels and CD4+/CD8+value in the observation group were increased when compared with those before treatment and higher than those in the control group in the same period,differences being significant(P<0.05).Compared CD8+levels in both groups and CD4+levels,CD4+/CD8+value in the control group before and after treatment, there was no significance in differences(P>0.05).ConclusionHuaiqihuang granules combined with prednisone acetate tablets has significant effect in treating children nephrotic syndrome of qi-yin deficiency type,which can effectively relieve clinical symptom and improve immune function of children.

    参考文献
    相似文献
    引证文献
引用本文

王军.槐杞黄颗粒联合醋酸泼尼松片治疗气阴两虚型小儿肾病综合征临床观察[J].新中医,2018,50(2):93-95

复制
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期: 2018-02-08
  • 出版日期: