天王补心汤联合穴位埋线治疗阴虚火旺型亚健康失眠疗效观察
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R256.23

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温州市2016年公益性科技计划项目(Y20160201)


Clinical Observation of Tianwang Buxin Tang Combined with Acupoint Catgut-Embedding Therapy for Sub-Health Insomnia of Fire Due to Yin Deficiency Type
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    摘要:

    目的:观察天王补心汤联合穴位埋线治疗阴虚火旺型亚健康失眠的临床疗效。方法:采用单盲、随机对照研究方法,将70例阴虚火旺型亚健康失眠患者分为试验组和对照组,每组35例。试验组予口服天王补心汤联合穴位埋线治疗,对照组予口服天王补心汤治疗,治疗后观察2组匹兹堡睡眠质量指数量表(PSQI)评分、WHO生活质量测定量表简明版(WHOQOL-BREF)评分、多导睡眠图指标的变化。结果:治疗后,2组PSQI各单项评分及总分均较治疗前降低(P<0.05);试验组睡眠质量、睡眠时间、日间功能及PSQI总分均低于对照组(P<0.05);2组入睡时间、睡眠效率、睡眠障碍评分比较,差异均无统计学意义(P>0.05)。治疗后,2组生理、心理、环境、社会关系评分均较治疗前升高(P<0.05);试验组4项评分均高于对照组(P<0.05)。治疗后,2组总睡眠维持时间、睡眠效率、REM及S3+S4均较治疗前增加(P<0.05),总觉醒次数、总觉醒时间、睡眠潜伏期时间均较治疗前减少(P<0.05);试验组总觉醒次数、总觉醒时间均少于对照组(P<0.05),REM及S3+S4均高于对照组(P<0.05)。结论:天王补心汤联合穴位埋线治疗阴虚火旺型失眠,能显著改善患者的睡眠及生活质量,临床效果好且安全性高,其作用机制可能与减少患者的觉醒次数及觉醒时间,增加深睡眠、快速动眼睡眠时间有关。

    Abstract:

    Objective:To observe the clinical effect of Tianwang Buxin tang combined with acupoint catgut-embedding therapy for sub-health insomnia of fire due to yin deficiency type.MethodsAdopted randomized single-blind trial, and divided 70 cases of patients with sub-health insomnia of fire due to yin deficiency type randomly into the experiment group and the control group,35 cases in each group.The experiment group receivedthe oral treatment of Tianwang Buxin tang combined with acupoint catgut-embedding therapy,while the control group received the oral treatment of Tianwang Buxin tang only.After treatment,observed the changes of scores of Pittsburgh sleep quality index(PSQI),scores of World Health Organization quality-of-life scale(WHOQOL-BREF), and index of polysomnography(PSG).ResultsAfter treatment, the single scores and total scores of PSQI in both group were all lower than those before treatment(P < 0.05);the total scores of sleep quality,sleep duration,daytime dysfunction and PSQI in the experiment group were all lower than those in the control group(P < 0.05);compared the total scores of the time for falling asleep,sleep efficiency and sleep disorder in the two groups,no significantdifference was found(P > 0.05).After treatment,scores of physiology,psychology,environment and social relations in both groups were higher than those before treatment(P < 0.05);the four scores in the experiment group were all higher than those in the control group(P < 0.05).After treatment,the total sleep maintenance time,sleep efficiency,REM and S3+S4 in both groups were all increased,comparing with those before treatment(P < 0.05),and the total number of awakening times,the total time of awakening and sleep latency were all reduced,comparing with those before treatment(P < 0.05);the total number of awakening times and the total time of awakening in the experiment group were both lower than those in the control group(P < 0.05),and REM as well as S3+S4 in the experiment group were both higher than those inthe control group(P<0.05).ConclusionTianwang Buxin tang combined with acupoint catgut-embedding therapy can significantly improve both the sleep and quality of life in treating sub-health insomnia of fire due to yin deficiency type,with good clinical effect and high safety.Its functioning mechanism may be related to reducing the times of wakening and the awakening time as well as increasing the time of deep sleep and rapid eye movement sleep.

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吴旭杰,李玮,吴志敏,黎斌,赵娜,胡万华.天王补心汤联合穴位埋线治疗阴虚火旺型亚健康失眠疗效观察[J].新中医,2018,50(2):108-111

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  • 在线发布日期: 2018-02-08
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