Objective：To observe the clinical effect of herbal fumigation combined with acupuncture for old ankle sprain.MethodsSelected 110 cases of patients with old ankle sprain as study subjects，and divided them into the observation group and the control group according to the random number table method，55 cases in each group.The control group receivedacupuncture therapy，while the observation group additionally received herbal fumigation based on treatment of the control group.Both groups received continuous treatment for three courses.After treatment，comprehensively evaluated the improvement of pain of affected side，swelling and function of ankle and therapeutic safety of both groups.ResultsThe totaleffective rate was 90.91%in the observation group and was 76.36%in the control group，the difference being significant(P＜0.05).Before treatment， no significant difference was found in the comparisons of visual analogue scales(VAS)， American orthopedic foot and ankle scores(AOFAS)and range of motion(ROM)between two groups(P ＞ 0.05).After treatment，scores of VAS in both groups were decreased in comparison with those before treatment(P ＜ 0.05)，while the scores of AOFAS and ROM were all increased(P＜0.05).The scores of VAS in the observation group were lower than those in the control group(P＜0.05)，while the scores of AOFAS and ROM were higher(P ＜ 0.05).Incidence of adverse reaction was 10.91%(6/55)in the observation group and was 5.45%(3/55)in the control group，there being no significant difference(P ＞ 0.05).ConclusionThe therapy of herbal fumigation combined with acupuncture has significant clinical effects in treating old ankle sprain.It can alleviate the pain，improve the range of motion and has good therapeutic safety and higher clinical value，which is worthy of further promotion and application.