Objective：To explore and analyze the administration rule of Chinese medicinefor adult onset still's disease(AOSD).Methods： China national knowledge internet(CNKI)， VIP Journal Integration Platform(VIP)and China Science Periodical Database(Wanfang data)were searched to sort out related literatures and establish a database.The administration rule of Chinese medicine for AOSD was analyzed via statistical software.Results：Among 47 pieces of literature for AOSD，229 kinds of Chinese medicine and 1153 times of administration frequency were found.The top 5 medications applied in single medicine in terms of administration frequency were radix glycyrrhiza(3.04%)，rhizoma anemarrhenae(2.95%)， cortex moutan(2.60%)， radix scutellariae(2.60%)and dried radix rehmanniae(2.60%).In terms of efficiency， heat-clearing medicine(35.76%)accounted for the biggest frequency， followed by tonifying medicine(18.48%)， exterior-releasing medicine(9.38%)， dampness-draining medicine(9.11%)， and wind-dampness-dispelling medicine(5.72%).Heat-clearing medicine mainly included heat-clearing and detoxifying medicine as well as heat-clearing and blood-cooling medicine.Tonifying medicine mainly included qi-tonifying medicine and yin-tonifying medicine.Conclusion：Treatment for AOSD has its own characteristics.The medication mainly focuses on heat-clearing medicine to detoxify and cool blood，as well as tonifying medicine to tonify qi and nourish yin，which combined with exterior-releasing medicine， dampness-draining medicine，wind-dampness-dispelling medicine and other medicine.