Objective： To observe the clinical effect of Qiju Dihuang pills combined with losartan potassium tablets for menopause insomnia with hypertension.Methods：Selected 116 cases of menopause female patients suffering from insomnia with hypertension and syndromes of kidney yin deficiency，and divided them into the control group and the observation group randomly，58 cases in each group.The control group took losartan potassium tablets and estazolam tablets for treatment，while the observation group took Qiju Dihuang pills and losartan potassium tablets for treatment.Both groups continuously receivedthe treatment for 4 weeks.Observed the clinical effect of patients in both groups after treatment，pittsburgh sleep quality index(PSQI)scores，and changes of blood pressure as well as adverse reaction in the treatment.Results：After treatment，the total effective rate was 94.8%in the observation group and 75.9%in the control group，the difference being significant(P ＜ 0.05).PSQI scores in the sleep time，time for falling asleep，sleep disorders，sleep efficiency，and daytime function of both groups were all lower than those before treatment(P＜0.05).Each index in the observation group was lower than that in the control group(P＜0.05).Diastolic blood pressure and systolic pressure of two groups were both improved when comparing with those before treatment(P ＜ 0.05)；diastolic blood pressure and systolic pressure of the observation group were both lower than those of the control group(P＜0.05).Conclusion：The application of Qiju Dihuang pills combined with losartan potassium tablets for patients of menopause insomnia with hypertension and kidney yin deficiency syndrome can improve sleep and blood pressure of patients，and its curative effect is better than that with losartan potassium combined with estazolam.