Objective： To observe the effect of modified Xiangsha Liujunzi tang on postoperative enteral nutrition of patients with colon cancer.Methods：Divided 189 cases of patients with colon cancer after the treatment of colon carcinoma operation into the observation group being 100 cases and the control group being 89 cases randomly.The control group received enteral nutrition support of TPF 24 hours after operation，while the observation group was additionally treated with modified Xiangsha Liujunzi tang.Before operation and on the 7thand 14thday of treatment after operation，detected blood routine， T-lymphocyte subsets， nutritional indexes[albumin(Alb)， prealbumin(PAlb)， hemoglobin(Hb)]， C-reactive protein(CRP)，and immunoglobulin(IgA，IgG，and IgM)，and recorded the time of first exhaust and time of defecating as well as adverse reaction.Results：On the 7thand 14thday after operation，WBC in the observation group were lower than those in the control group，differences being significant(P ＜ 0.05).On the 7thand 14thday after operation，RBC，PAlb，and IgA in the observation group were all higher than those in the control group.On the 7thand 14thday after operation，BPC in the observation group was higher than that in the control group，while on the 14thday after operation Alb in the observation group was higher than that in the control group，differences being significant(P＜0.05).Hb levels in the two groups had no obvious changes，and there were no significant differences being found in the comparisons of two groups before and after operation and the inter-group comparison(P ＞ 0.05).On the 14thday after operation，CD3+，CD4+，and CD4+/CD8+in the observation group were all higher than those in the control group，and on the 7thday after operation CD3+，CD4+，and CD4+/CD8+in the observation group were all higher than those in the control group，differences being significant(P＜0.05).IgM in the observation group on the 7thday after operation and IgG and IgM on the 14thday after operation were all higher than those in the control group in the same period，differences being significant(P＜0.05).CRP in the observation group increased seven days after operation and dropped to the preoperative level on the 14thday after operation，both of which were lower than those in the control group，differences being significant in the comparisons of two groups before and after operation and the inter-group comparison(P ＜ 0.05).The time of first exhaust，time of first defecating，and rate of gastrointestinal adverse reaction in the observation group were all lower and less than those in the control group，differences being significant(P＜0.05).Conclusion：The therapy of modified Xiangsha Liujunzi tang has a positive effect on postoperative enteral nutrition of patients with colon cancer， can improve conditions of patients with immune deficiency and nutritional deficiencies， and reduce recovery time of patients and the incidence of adverse reaction，thus to improve quality of life.