Objective：To observe theclinical effect of integrated Chinese and western medicine for pulmonary embolism.Methods：Selected 80 cases of patients with pulmonary embolism as study subjects，and divided them into the Chinese and western medicine group and the western medicine group according to the principle of randomized control，40 cases in each group.The Chinese and western medicine group was given Chinese medicine decoction combined with western medicine for treatment，while the western medicine group was simply given western medicine for treatment.Compared the therapeutic effect between the two groups after treatment.Results：The total effective rate was 92.50%in the Chinese and western medicine group and was 70.00%in the western medicine group，the difference being significant(P＜0.05).After treatment，the partial pressure of oxygen(PO2)and the partial pressure of carbon dioxide(PCO2)in the two groups were improved when compared with those before treatment(P＜0.05).The improvement of the two indexes in the Chinese and western medicine group was better than that in the western medicine group(P＜0.05).The amount of anticoagulant used to achieve target value of the international normalized ratio(INR)during the prothrombin time(PT)in the Chinese and western medicine group was less than that in the western medicine group，and the standard time in the Chinese and western medicine group was shorter than that in the western medicine group，differences being significant(P＜0.05).Conclusion：The therapy of integrated Chinese and western medicine for pulmonary embolism can effectively improve the clinical symptoms of patients and reduce the dosage of anticoagulant，which is superior to the treatment of simple western medicine.