加味化肝煎结合三联疗法治疗 Hp 阳性慢性胃炎临床观察
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R573.3

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Clinical Observation on Modified Huaganjian Combined with Triple Therapy for Hp Positive Chronic Gastritis
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    摘要:

    目的:观察加味化肝煎结合三联疗法治疗肝胃郁热型幽门螺杆菌(H p)阳性慢性胃炎的临床疗效。方法:选取80例肝胃郁热型H p阳性慢性胃炎患者,随机分为对照组和实验组各4 0例。对照组采用三联疗法治疗,实验组采用加味化肝煎结合三联疗法治疗。比较2组临床疗效,观察患者治疗前后血清胃蛋白酶原Ⅰ(P GⅠ),P GⅡ及胃泌素-17(G-17)的变化。结果:对照组总有效率7 5.0%,实验组总有效率9 0.0%,2组比较,差异有统计学意义(P<0.05)。治疗前,2组G-17、P GⅠ及P GⅡ水平比较,差异均无统计学意义(P>0.05)。治疗后,2组G-17、P GⅠ及P GⅡ水平均较治疗前降低,差异均有统计学意义(P<0.05);实验组G-17、P GⅠ及P GⅡ水平均低于对照组,差异均有统计学意义(P<0.05)。结论:加味化肝煎结合三联疗法治疗肝胃郁热型H p阳性慢性胃炎疗效显著,可有效减轻患者的胃黏膜病变情况,增强胃肠道功能。

    Abstract:

    Objective:To observe the clinical effect of modified Huaganjian combined with triple therapy for helicobacterpylori(Hp)positive chronic gastritis of stagnated heat in liver and stomach type.M e th o d s:Selected 80 cases of patients with Hp positive chronic gastritis of stagnated heat in liver and stomach type,and divided them into the control group and the experiment group randomly,40 cases in each group.The control group received triple therapy while the experiment group was given modified Huaganjian combined with triple therapy for treatment.Compared the clinical effect of the two groups,and observed the changes of pepsinogen I(PGⅠ),PGⅡ and gastrin-17(G-17)in serum before and after treatment.R e s u lts:The total effective rate was 75.0%in the control group and was 90.0%in the experiment group,the difference being significant(P< 0.05).Before treatment,compared levels of G-17,PGⅠand PGⅡ in the two groups,there was no significance in the difference(P< 0.05).After treatment,levels of G-17,PGⅠand PGⅡin the two groups were decreased when compared with those before treatment,differences being significant(P<0.05).Levels of G-17,PGⅠand PGⅡ in the experiment group were lower than those in the control group,differences being significant(P < 0.05).Conclusion:The therapy of modified Huaganjian combined with triple therapy has significant curative effect in treating Hp positive chronic gastritis of stagnated heat in liver and stomach type,which can effectively reduce the gastric mucosal lesions of patients and enhance gastrointestinal function.

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史继波,徐清喜.加味化肝煎结合三联疗法治疗 Hp 阳性慢性胃炎临床观察[J].新中医,2018,50(6):163-165

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  • 在线发布日期: 2018-06-05
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