姜汁法夏散穴位贴敷联合托烷司琼治疗恶性血液病化疗所致恶心呕吐临床研究
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R552

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广州中医药大学第一附属医阮2015年度”创新强院”工程科研系列项目(2015HL05)


Clinical Study of Point-application with Jiangzhi Faxia Powder Combined with Tropisetron for Nausea and Vomiting Caused by Hematologic Malignancies Under Chemotherapy
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    摘要:

    目的:观察姜汁法夏散穴位贴敷联合托烷司琼治疗恶性血液病化疗所致恶心呕吐的临床疗效。方法:将206例恶性血液病患者随机分为试验组115例和对照组9 1例。对照组给予静脉注射托烷司琼、常规护理和安慰剂穴位贴敷,试验组在对照组基础上配合姜汁法夏散穴位贴敷,每天1次,治疗从化疗当天开始至化疗结束(一般为3~7天)。比较2组患者化疗开始后12 h、第1天、第2天、第3天、第4天、第5天、第6天呕吐发生率、呕吐程度、恶心发生率、恶心程度。结果:化疗开始后12 h、第1天、第2天,试验组呕吐发生率均低于对照组(P<0.05),而在第3天、第4天、第5天、第6天时,试验组呕吐发生率与对照组比较均无差异(P>0.05);化疗开始后各时间段,试验组呕吐程度均较对照组轻(P<0.05);试验组恶心发生率及恶心程度亦较对照组改善(P<0.05)。结论:姜汁法夏散穴位贴敷联合托烷司琼能有效缓解恶性血液病患者化疗所致恶心、呕吐。

    Abstract:

    Objective: To observe the clinical effect of point-application with Jiangzhi Faxia powder combined with tropisetron for nausea and vomiting caused by hematologic malignancies under chemotherapy.M e th o d s:Divided 206 cases of patients with hematologic malignancies into the test group being 115 cases and the control group being 91 cases randomly.The control group was given intravenous injection of tropisetron,routine nursing and placebo point-application,while the test group was additionally given point-application with Jiangzhi Faxia powder for treatment,once a day.The treatment lasted from the beginning of chemotherapy to its end(usually three to seven days).Compared the incidence of vomiting,degree of vomiting,incidence of nausea and degree of nausea of patients in the two groups after the start of chemotherapy for 12 h,1,2,3,4,5 and 6 days.Results:After the start of chemotherapy for12 h,1 and 2 days,the incidence of vomiting in the test group was lower than that in the control group(P < 0.05),while on 3,4,5,and 6 days of chemotherapy,there were no significant differences being found in the comparisons of incidence of vomiting between the test group and the control group(P>0.05).During each period of time after the start of chemotherapy,the degree of vomiting in the test group was lower than that in the control group(P < 0.05),and the incidence of vomiting and degree of nausea in the test group were also lower than those in the control group(P<0.05).Conclusion:The therapy of point-application with Jiangzhi Faxia powder combined with tropisetron can effectively relieve nausea and vomiting caused by chemotherapy in patients with hematological malignancies.

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张泱悦,朱向定,田遂芬,高静,陈达,徐景利.姜汁法夏散穴位贴敷联合托烷司琼治疗恶性血液病化疗所致恶心呕吐临床研究[J].新中医,2018,50(6):169-172

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  • 在线发布日期: 2018-06-05
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