Objective：To observe the clinical effect of Kaijiang Fenxiao tang combined with routine western medicine for coronary heart disease.Methods：Divided 160 cases of patients with coronary heart disease with phleg mstag nation syndrome admitted in our hospital into the study group and the control group randomly，80 cases in each group.The two groups received routine western medicine as isosorbide mononitrate tablets and bayaspirin for treatment，while the study group additionally received Kaijiang Fenxiao tang.The two groups received treatment for four weeks.Compared the clinical effect in the two groups and observed the changes of blood lipids indexes which include total cholesterol(TC)，triglyceride(TG)，high density lipoprotein cholesterol(HDL-C)and lowdensity lipoprotein cholesterol(LDL-C)and changes of C-reactive protein(CRP)，homocysteine(Hcy)and Chinese medicine syndrome scores before and after treatment.Results：After treatment，HDL-C level in the two groups was higher than that before treatment(P ＜ 0.05)，while levels of LDL-C，CRP and Hcy were lower than those before treatment( P ＜0.05)and TC level in the study group was lower than that before treatment( P ＜0.05)；levels of LDL-C，CRP and Hcy in the study group were lower than those in the control group(P ＜ 0.05)，while HDL-C level in the study group was higher than that in the control group(P ＜ 0.05).Scores of chest pain，chest distress，dyspnea，palpitation，hypochondriu mfullness，tongue manifestation and pulse manifestation in the two groups were decreased when compared with those before treatment( P ＜ 0.05)，and all scores in the study group were lower than those in the controlgroup( P ＜ 0.05).The clinical effect and electrocardiogramefficacy in the study group were superior to those in the control group，differences being significant( P ＜ 0.05).Conclusion：Based on the routine western medicine，additional administration of Kaijiang Fenxiao tang for patients with coronary heart disease with phlegmstagnation syndrome can further relieve inflammation，improve Chinese medicine syndrome and improve the clinicaleffect.