Objective：To observe the clinical effect of method of strengthening earth to generate metal combined with western medicine for peripheral skeletal muscle dysfunction of chronic obstructive pulmonary disease(COPD)in the stable stage.Methods：Selected 72 cases of patients with peripheral skeletal muscle dysfunction of COPD with qi deficiency of lung-spleen type in the stable stage and divided theminto the observation group and the controlgroup randomly，36 cases in each group.The control group was given inhalation therapy of budesonide/formoterol single inhaler for treatment，while the observation group was additionally given the prescription ofmethod of strengthening earth to generate metal for intervention.Observed the clinical effect and changes of lung function indexes like forced expiratory volume in one second(FEV 1 %pred)，forced vital capacity FEV 1 %(FEV 1 /FVC)， 6 min walking test(6MWT)， quadriceps maximu mvoluntary contraction(QMVC)and hand grip strength(HGS)before and after treatment in the two groups.Results：After treatment，the totaleffective rate in the observation group was higher than that in the control group，difference being significant(P ＜ 0.05).6 min walking distance，FEV 1 %pred，FEV 1 /FVC，QMVC and HGS in the two groups were all increased when compared with those before treatment，and those five indexes in the observation group were all higher than those in the control group，differences being significant( P ＜0.05).Conclusion：The method of strengthening earth to generate metal has a function of strengthening the spleen and benefiting the lungs so as to improve the muscle strength.The combination therapy can better improve the clinical symptoms of the peripheral skeletal muscle dysfunction of COPD in the stable stage， improve the curative effect， and has certain significance in clinicalguidance.