Objective：To observe the clinical effect of treatment for functional constipation in children based on Chinese medicine syndrome differentiation and tuina manipulation.Methods：Selected 80 cases of children with functional constipation，and divided theminto the controlgroup and the treatment group randomly，40 cases in each group.The control group was given routine western medicine for treatment，while the treatment group was additionally given syndrome differentiation tuina manipulation for treatment.After five days of treatment， compared the clinical effect， evaluated the Chinese medicine syndrome scores of pediatric constipation of excess syndrome type and deficiency syndrome type and constipation symptomscore，and compared the occurrence of adverse reactions and the recurrence rate after the follow-up of 3 months in the two groups.Results：After treatment，the total effective rate was 97.5%in the treatment group and 77.5%in the controlgroup，difference being significant(P ＜ 0.05).After treatment，the Chinese medicine syndrome scores of pediatric constipation of excess syndrome type and deficiency syndrome type，constipation symptomscores in the two groups were all decreased when compared with those before treatment( P ＜0.05).The decrease of each score in the treatment group was more obvious than that in the control group( P ＜0.05).The incidence of adverse reactions was 7.5%in the treatment group and 47.5%in the control group，difference being significant( P ＜0.05).The recurrence rate after the follow-up of 3 months was 7.5%in the treatment group and 20.0%in the control group，difference being significant( P ＜0.05).Conclusion：The therapy based on Chinese medicine syndrome differentiation and tuina manipulation has a significant effect in treating functional constipation in children，which can improve the symptoms of Chinese medicine and relieve constipation with fewer adverse reactions and recurrences.