Objective： To observe the curative effect of the external application of Chinese medicine in promoting rehabilitation of patients after painless tooth extraction.Methods：Collected 90 cases of patients who received the extraction of impacted wisdomtooth in our department of dentistry，and divided theminto the treatment group and the control group randomly，45 cases in each group.Both groups pumped intravenous propofol injection so as to extract the tooth by applying the target-controlled infusion.The control group was given cefixime tablets and tinidazole tablets orally and continuously for three days after tooth extraction，while the treatment group additionally received the externalapplication of Chinese medicine continuously for seven days after two hours of the tooth extraction(honeysuckle，chrysanthemum，weeping forsythia，isatis root， dyers woad leaf， red peony root， patrinia).Compared the quality of life of patients after tooth extraction[applied postoperative symptoms severity scale(PoSSe)]and pain intensity[applied pain visual analogue scale(VAS)]in the two groups，and counted the incidence of adverse reaction.Results：After three days of treatment，the VAS score in the treatment group was lower than that in the control group(P ＜ 0.01).After seven days of treatment，there was no significant difference being found in the comparison of VAS scores in the two groups(P ＞ 0.05).After seven days of treatment，scores of speech，diet，swelling and daily life in the treatment group were lower than those in the control group( P ＜0.01).The incidence of adverse reaction was 17.78% in the treatment group，being higher than that of 33.33% in the control group， difference being significant( P ＜0.01).Conclusion：The external application of Chinese medicine has an effect of improving quality of life and obviously reducing pain of patients after painless tooth extraction and its safety is significant.