Objective：To observe the clinical effect of acupotomy lysis on psoas major combined with positive clustered nodules points of waist and hip for lumbar disc herniation.Methods：Divided 60 cases of patients with lumbar disc herniation into two groups randomly，30 cases in each group.The treatment group received acupotomy lysis on psoas major combined with positive clustered nodules points of waist and hip for treatment，while the control group received acupotomy lysis on positive clustered nodules points of waist and hip.Recorded JOA scores of patients respectively before treatment and after treatment of 12 days and conducted statisticalanalysis.Results：Compared with those before treatment，scores of Japanese Orthopedic Association(JOA)lowback pain rating scale in the two groups were increased after treatment，differences being significant(P ＜ 0.05).After treatment，JOA score in the treatment group was higher than that in the control group，the difference being significant( P ＜0.05).The cured and marked ly effective rate of clinical effect was 83.3%in the treatment group and was 70.0%in the control group，the difference being significant(P ＜ 0.05).Conclusion：The clinical effect of the therapy of acupotomy lysis on psoas major combined with positive clustered nodules points of waist and hip for lumbar disc herniation is superior to that of the simple therapy of acupotomy lysis on positive clustered nodules points ofwaist and hip.