Clinical Observation of Zhichan Tang Combined with Auricular Acupoint Pressing with Beans for Parkinson's Disease Accompanying Sleep Disorder
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摘要:
目的:观察止颤汤联合耳穴压豆治疗帕金森病(PD)伴睡眠障碍的临床疗效。方法:将60例PD伴睡眠障碍患者随机分为止颤汤组、耳穴压豆组及联合治疗组各20例。3组均给予PD基础治疗,而后根据不同的中医治疗方法进行治疗,均持续治疗4周。治疗后采用多导睡眠图(PSG)、匹兹堡睡眠质量指数量表(PSQI)及爱泼沃斯嗜睡量表(ESS)对睡眠情况进行评估。结果:治疗后,联合治疗组卧床时间和总睡眠时间均长于止颤汤组和耳穴压豆组( P <0.05),睡眠效率均高于止颤汤组和耳穴压豆组( P <0.05),睡眠潜伏期和觉醒次数均低于止颤汤组和耳穴压豆组( P <0.05)。3组Ⅱ期、Ⅲ期睡眠时间及深度睡眠时间(SWS)比较,差异均无统计学意义(P>0.05)。治疗前,3组PSQI、ESS评分比较,差异均无统计学意义(P>0.05)。治疗后,联合治疗组PSQI、ESS评分均低于止颤汤组和耳穴压豆组,差异均有统计学意义( P <0.05)。结论:联合治疗组治疗PD伴睡眠障碍较止颤汤组和耳穴压豆组治疗效果更显著。
Abstract:
Objective:To observe the clinical effect of Zhichan tang combined with auricular acupoint pressing with beans for Parkinson's disease(PD)accompanying sleep disorder.Methods:Divided 60 cases of patients with PD accompanying sleep disorder into the Zhichan tang group,the group of auricular acupoint pressing with beans and the combined treatment group randomly,20 cases in each group.The three groups all received the basic treatment for PD,and then were given the different therapeutic methods in Chinese medicine for treatment.The treatment of each group lasted for 4 weeks.After treatment,evaluated sleep conditions by adopting polyso mnography(PSG),Pittsburgh sleep quality index(PSQI)and Epworth sleepiness scale(ESS).Results:After treatment,the bed rest time and the total sleep time in the combined treatment group were both longer than those in the Zhichan tang group and the group of auricular acupoint pressing with beans(P < 0.05),the sleep efficacy was higher than that in the Zhichan tang group and the group of auricular acupoint pressing with beans respectively(P < 0.05),and the sleep latency and awakening times were all lower than those in the Zhichan tang group and the group of auricular acupoint pressing with beans( P <0.05).Comparing the sleep time and slowwave sleep(SWS)time at stage IIand III in-between the three groups,there were no differences being found(P > 0.05).Before treatment,comparing the scores of PSQIand ESS in-between the three groups,there were no differences being found(P > 0.05).After treatment,the scores of PSQIand ESS in the combined treatment group were all lower than those in the Zhichan tang group and the group of auricular acupoint pressing with beans,differences being significant( P < 0.05).Conclusion:The combined treatment group has more significant clinicaleffect,compared with the groups of Zhichan tang or auricular acupoint pressing with beans.