Objective：To observe the clinical effect of acupotomy lysis combined with block therapy for pop liteal bursitis.Methods：Selected 60 cases of patients with popliteal bursitis，and divided theminto the treatment group and control group randomly，30 cases in each group.The treatment group received the acupotomy lysis combined with block therapy，while the controlgroup received the block therapy.The two groups both received the treatment once.2 weeks and 3 months after treatment，respectively compared the clinicaleffect in both groups.Evaluated the scores of visualanalogue scale(VAS)before treatment and 2 weeks and 3 months after treatment.Results：2 weeks after treatment，the totaleffective rate was 93.33%in the treatment group and 90.00%in the control group，difference being insignificant(P ＞ 0.05)；3 months after treatment，the total effective rate was 93.33%in the treatment group and 73.33%in the control group，difference being significant( P ＜0.05).2 weeks and 3 months after treatment，scores of VAS in both groups were lower than those before treatment(P ＜0.05)；2 weeks after treatment， there was no significant difference being found in the scores of VAS of both groups(P ＞0.05)； 3 months after treatment， scores of VAS in the treatment group were lower than those in the control group，difference being significant( P ＜0.05).Conclusion：Acupotomy lysis combined with block therapy has definite clinicaleffect in treating poplitealbursitis，which can alleviate the pain of patients with comparatively long-lasting clinicaleffect.