Objective：To observe the curative effect and the adverse reactions of Bushen tang com bined with alendronate sodium tablets for prim ary osteoporosis with kidney deficiency type.Methods：Selected 156 cases of patients with prim ary osteoporosis with kidney deficiency type as study objects and divided theminto the treatment group and the control group randomly，88 cases in each group.The control group received anti-osteoporosis western medicine of alendronate sodium tablets for treatment，while the treatment group additionally received Chinese medicine of Bushen tang based on the treatment of the control group.Compared the scores of visual analogue scale(VAS)，bone mineral density and the clinical effect in the two groups.Results：The total effective rate was 76.2%in the treatment group and was 69.3%in the control group，the difference being significant( P ＜0.05).After treatment，VAS scores in the two groups were significantly decreased when compared with those before treatment( P ＜0.01)，and the VAS score in the treatment group was lower than that in the control group( P ＜0.05).After treatment，bone mineral density in each part in the two groups was significantly improved when compared with that before treatment( P ＜0.01)，and bone mineral density in the treatment group was larger than that in the controlgroup( P ＜0.05).After treatment，compared with the changes of relevant indexes of bone in serum as calcium and phosphorus and the changes of liver and kidney functions，there was no significance in the difference( P ＞0.05).Conclusion：The therapy of Bushen tang com bined with alendronate sodium tablets for prim ary osteoporosis with kidney deficiency type is superior to that of simple alendronate sodium tablets.It can better improve the clinical symptoms and body signs，increase bone mineraldensity of patients，which is worthy of promotion and application in clinicalpractice.