射干麻黄汤治疗寒饮停肺型小儿咳嗽变异性哮喘临床分析
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R725.6

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Clinical Analysis on Shegan Mahuang Tang for Child ren with Cough Varian t Asthm a with Synd rome of Co ld Fluid Retaining in the Lung
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    摘要:

    目的:观察射干麻黄汤联合孟鲁司特治疗寒饮停肺型小儿咳嗽变异性哮喘的临床疗效。方法:将60例患儿随机分为2组各30例,对照组给予孟鲁司特治疗,观察组在对照组基础上联合射干麻黄汤治疗,观察比较2组临床疗效、肺功能[第1秒用力呼气容积变化(FEV 1 )、用力肺活量(FVC)、最大呼气峰流速百分比(PEF)]以及治疗过程中出现的不良反应情况。结果:总有效率观察组为93.33%,对照组为73.33%,2组比较,差异有统计学意义( P <0.05)。治疗后,2组患者FEV 1 、FVC、PEF均较治疗前明显改善( P <0.05);且观察组FEV 1 、FVC、PEF改善较对照组更显著( P <0.05)。不良反应总发生率观察组为3.33%,对照组为20.00%,2组比较,差异有统计学意义( P <0.05)。结论:采用射干麻黄汤联合孟鲁司特治疗寒饮停肺型小儿咳嗽变异性哮喘,可提高临床效果,改善患儿肺功能,疗效优于单纯孟鲁司特。

    Abstract:

    Objective:To observe the clinicaleffect of Shegan Mahuang tang com bined with montelukast for children with cough variant asthm a with syndrome of cold fluid retaining in the lung.Methods:Divided 60 cases of children into two groups randomly,30 cases in each group.The control group was given montelukast,while the observation group was additionally given Shegan Mahuang tang.Observed and analyzed the clinical effect,pulmonary functions[changes of forced expiratory volume in one second(FEV 1 ), forced vital capacity(FVC), peak expiratory flow rate(PEF)]and the occurrence of adverse reactions in both groups.Results:The total effective rate was 93.33%in the observation group and 73.33%in the control group,difference being significant( P <0.05).After treatment,FEV 1 ,FVC and PEF in both groups were significantly improved when comparing with those before treatment( P <0.05);and FEV 1 ,FVC and PEF in the observation group were improved more significantly than those in the control group( P <0.05).The total incidence of adverse reactions was 3.33%in the observation group and 20.00%in the control group,difference being significant( P <0.05).Conclusion:The application of Shegan Mahuang tang com bined with montelukast treating children with cough variant asthm a with syndrome of cold fluid retaining in the lung can promote the clinical effect and improve the pulmonary functions of patients,which has better therapeutic effect than the treatmentwith simple montelukast.

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寇东灿,王宏权,钱春莉,张军辉.射干麻黄汤治疗寒饮停肺型小儿咳嗽变异性哮喘临床分析[J].新中医,2018,50(9):131-133

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  • 在线发布日期: 2018-09-04
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