Headache is a common and frequently-occurring disease in Chinese medicine encephalopathy.In Chinese medicine，headaches caused by internal dam age are closely related to the liver in physiological and pathological aspects.The authors tried to treat the headache caused by internal dam age through the liver.If the liver qi is stagnated，the method of soothing the liver and regulating the circulation of qi should be applied.For those who suffered from the obstruction of liver blood stasis，the method of promoting blood circulation to remove meridian obstruction should be adopted.For those with hyperactivity of liver yang，the method of calming the liver and suppressing yang should be used.For those with liver blood deficiency，the method of replenishing blood and nourishing liver should be applied，and for those with deficiency of the liver and kidney，the method of reinforcing the spleen and the kidney should be adopted.A clinical trialwas conducted to verify the specific application of dispersing liver and promoting blood circulation.