头痛宁胶囊联合阿司匹林治疗偏头痛临床观察
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R747.2

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Clinical Observation on Toutongning Capsules Combined with Aspirin for Migraine
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    摘要:

    目的:观察头痛宁胶囊联合阿司匹林治疗偏头痛的临床疗效及安全性。方法:选取60例偏头痛患者为研究对象,按随机数字表法分为对照组和观察组,每组30例。对照组进行健康宣教的同时给予口服阿司匹林治疗,观察组在对照组基础上加服头痛宁胶囊,2组均连续治疗2周。对比2组临床疗效及治疗前后头痛发作次数、头痛持续时间及头痛程度,记录不良反应情况。结果:观察组治疗总有效率86.67%,高于对照组的63.33%,差异有统计学意义(P<0.05)。治疗后,2组头痛发作次数均较治疗前减少(P<0.05),头痛持续时间均较治疗前缩短(P<0.05),视觉模拟评分法(VAS) 评分均较治疗前降低(P<0.05);观察组头痛发作次数少于对照组(P<0.05),头痛持续时间短于对照组(P<0.05),VAS评分低于对照组(P<0.05)。对照组不良反应发生率10.00%,观察组不良反应发生率13.33%,2组比较,差异无统计学意义(P>0.05)。结论:头痛宁胶囊联合阿司匹林治疗偏头痛能提高临床疗效,且不良反应少,安全性高。

    Abstract:

    Objective:To observe the clinical effect of Toutongning capsules combined with aspirin for migraine and its safety.Methods:Selected 60 cases of patients with migraine as study subjects,and divided them into the control group and the observation group according to the random number table method,30 cases in each group.The control group was given health education and treated with oral administration of compound aspirin,while the observation group was additionally given Toutongning capsules based on the treatment of the control group.Both groups were treated for two weeks continuously.Compared the clinical effect,the times of headache attacks,and the duration as well as severity of headaches before and after treatment in the two groups,and recorded the adverse reactions.Results:The total effective rate in the observation group was 86.67%,higher than that of 63.33% in the control group,the difference being significant(P<0.05).After treatment,both groups had fewer headache attacks than before treatment(P<0.05); the duration of headache shortened when compared with that before treatment(P<0.05);scores of visual analogue scale(VAS)were decreased when compared with those before treatment(P<0.05).Compared with those in the control group respectively,the observation group had fewer headache attacks(P<0.05);the duration of headache was shorter(P<0.05);VAS score was lower(P<0.05).The incidence of adverse reactions was 10.00% in the control group and 13.33% in the observation group,there being no significant difference(P>0.05).Conclusion:The therapy of Toutongning capsules combined with aspirin for migraine can improve clinical effect with less adverse reactions and higher safety.

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周阳,刘荣荣.头痛宁胶囊联合阿司匹林治疗偏头痛临床观察[J].新中医,2018,50(12):63-65

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  • 在线发布日期: 2018-12-09
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